protein

Recombinant Human 40S ribosomal protein SA (RPSA)

MBS961110

1 mg (E Coli Derived

1635 USD

Recombinant Protein

Recombinant Human 40S ribosomal protein SA (RPSA)

40S ribosomal protein SA(RPSA)

40S ribosomal protein SA; 40S ribosomal protein SA; 40S ribosomal protein SA; 37 kDa laminin receptor; 67 kDa laminin receptor; 37/67 kDa laminin receptor; laminin-binding protein precursor p40; colon carcinoma laminin-binding protein; laminin receptor 1 (67kD, ribosomal protein SA); multidrug resistance-associated protein MGr1-Ag; ribosomal protein SA; 37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 67 kDa laminin receptor; Colon carcinoma laminin-binding proteinLaminin receptor 1; Laminin-binding protein precursor p40

RPSA

RPSA; RPSA; SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4; LBP/p40

RSSA_HUMAN

E Coli or Yeast or Baculovirus or Mammalian Cell

2-295

295

SGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA TQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTDWS

>90%

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)

Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

59859885

NP_001012321.1

NM_001012321.1

P08865

32,854 Da

Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway 105970!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Cap-dependent Translation Initiation Pathway 105967!!Cytoplasmic Ribosomal Proteins Pathway 198853!!Disease Pathway 530764!!Eukaryotic Translation Elongation Pathway 105976!!Eukaryotic Translation Initiation Pathway 105966!!Eukaryotic Translation Termination Pathway 105978!!Formation Of A Pool Of Free 40S Subunits Pathway 105968!!Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway 105969

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

1 mg (E Coli Derived)

1635 USD