MUC2 Antibody | MyBioSource MBS9608759 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MUC2 Antibody

catalog :

MBS9608759

quantity :

0.1 mL

price :

240 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

MBS9608759 at 1/200 staining Rat colon tissue sections by IHC-P.

image 2 :

MBS9608759 staining SW480 cells by ICC/IF. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600 was used as secondary antibody.

image 3 :

Western blot analysis of MUC2 using HT-29 whole cell lysates

product information

catalog number :

MBS9608759

products type :

Antibody

products full name :

MUC2 Antibody

products short name :

[MUC2]

products name syn :

[Intestinal mucin 2; Intestinal mucin-2; MLP; MUC 2; MUC-2; Muc2; MUC2_HUMAN; Mucin 2; Mucin 2 intestinal; Mucin 2 intestinal/tracheal; Mucin 2 oligomeric mucus/gel forming; Mucin 2 precursor; Mucin 2 tracheal; Mucin like protein; Mucin-2; Mucin2; SMUC]

other names :

[Mucin-2; Mucin-2; mucin-2; mucin 2, oligomeric mucus/gel-forming; Intestinal mucin-2]

products gene name :

[MUC2]

other gene names :

[MUC2; MUC2; MLP; SMUC; MUC-2; SMUC; MUC-2]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

specificity :

MUC2 antibody detects endogenous levels of total MUC2

purity :

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

form :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

concentration :

1mg/ml

storage stability :

Store at -20 degree C. Stable for 12 months from date of receipt.

tested application :

Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)

app notes :

WB: 1:1000-3000. IHC: 1:50-1:200. IF/ICC: 1:100-1:500

image1 heading :

Immunohistochemistry (IHC)

image2 heading :

Immunofluorescene (IF)

image3 heading :

Western Blot (WB)

other info1 :

Immunogen: A synthesized peptide derived from human MUC2, corresponding to a region within N-terminal amino acids. Function: Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

products references :

Wang J, Lu J, Xie X, Xiong J, Huang N, Wei H, Jiang S, Peng J; Journal: Int Immunopharmacol. Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7.

ncbi gi num :

2506877

ncbi acc num :

Q02817.2

uniprot acc num :

Q02817

ncbi mol weight :

540 kDa

ncbi pathways :

Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); C-type Lectin Receptors (CLRs) Pathway (1269303); Dectin-2 Family Pathway (1269308); Defective C1GALT1C1 Causes Tn Polyagglutination Syndrome (TNPS) Pathway (1383050); Defective GALNT12 Causes Colorectal Cancer 1 (CRCS1) Pathway (1383052); Defective GALNT3 Causes Familial Hyperphosphatemic Tumoral Calcinosis (HFTC) Pathway (1383051); Disease Pathway (1268854); Diseases Associated With O-glycosylation Of Proteins Pathway (1383049); Diseases Of Glycosylation Pathway (1269010)

ncbi summary :

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]

uniprot summary :

Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

size1 :

0.1 mL

price1 :

240 USD

size2 :

0.2 mL

price2 :

280

more info or order :

MyBioSource product webpage