product summary
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company name :
MyBioSource
product type :
antibody
product name :
SEP15 Antibody
catalog :
MBS9608582
quantity :
0.1 mL
price :
240 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MBS9608582 at 1/100 staining Human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
image 2 :
Western blot analysis SEP15 using K562 whole cell lysates
product information
catalog number :
MBS9608582
products type :
Antibody
products full name :
SEP15 Antibody
products short name :
[SEP15]
products name syn :
[15 kDa selenoprotein; SELENOF; Selenoprotein F; Sep15; SEP15_HUMAN]
other names :
[selenoprotein F isoform 1; Selenoprotein F; selenoprotein F; selenoprotein F; 15 kDa selenoprotein1 PublicationManual assertion based on opinion iniRef.6"A new human selenium-containing protein. Purification, characterization, and cDNA sequence."Gladyshev V.N., Jeang K.-T., Wootton J.C., Hatfield D.L.J. Biol. Chem. 273:8910-8915(1998) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-165 (ISOFORM 1), PROTEIN SEQUENCE OF 101-109; 126-130 AND 149-161, TISSUE SPECIFICITY, MASS SPECTROMETRY.]
products gene name :
[SEP15]
products gene name syn :
[SELENOF]
other gene names :
[SELENOF; SELENOF; SEP15]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Rat
sequence length :
165
specificity :
SEP15 antibody detects endogenous levels of total 42628.
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:1000-3000. IHC: 1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human SEP15, corresponding to a region within the internal amino acids.
products description :
Function: May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity). Similarity: Belongs to the selenoprotein M/F family.
ncbi gi num :
42741648
ncbi acc num :
NP_004252.2
ncbi gb acc num :
NM_004261.4
uniprot acc num :
O60613
ncbi mol weight :
18 kDa
ncbi pathways :
Selenium Pathway (198825)
ncbi summary :
The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2016]
uniprot summary :
May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum ().
size1 :
0.1 mL
price1 :
240 USD
size2 :
0.2 mL
price2 :
280
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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