catalog number :
MBS960741
products type :
Recombinant Protein
products full name :
Recombinant Human Blood group Rh (D) polypeptide (RHD)
products short name :
Blood group Rh (D) polypeptide (RHD)
products name syn :
Recombinant Blood group Rh (D) polypeptide (RHD); Blood group Rh(D) polypeptide; RHXIII Rh polypeptide 2; RhPII Rhesus D antigen CD_antigen= CD240D
other names :
blood group Rh(D) polypeptide isoform 2; Blood group Rh(D) polypeptide; blood group Rh(D) polypeptide; blood group Rh(D) polypeptide; D antigen (DCS); RH polypeptide 2; rhesus D antigen; Rhesus system D polypeptide; Rh blood group antigen Evans; Rhesus blood group D antigen allele DIII type 7; Rh blood group, D antigen; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen
products gene name syn :
RHD
other gene names :
RHD; RHD; RH; Rh4; RH30; RhII; RhPI; DIIIc; RHCED; RHDel; RHPII; RhDCw; CD240D; RHXIII; RHDVA(TT); RhK562-II; RhPII
uniprot entry name :
RHD_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-417
sequence :
SSKYPRSVRRCLPLWALTLEAALILLFYFFTHYDASLED
QKGLVASYQVGQDLTVMAAIGLGFLTSSFRRHSWSSVAF
NLFMLALGVQWAILLDGFLSQFPSGKVVITLFSIRLATM
SALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVI
SNIFNTDYHMNMMHIYVFAAYFGLSVAWCLPKPLPEGTE
DKDQTATIPSLSAMLGALFLWMFWPSFNSALLRSPIERK
NAVFNTYYAVAVSVVTAISGSSLAHPQGKISKTYVHSAV
LAGGVAVGTSCHLIPSPWLAMVLGLVAGLISVGGAKYLP
GCCNRVLGIPHSSIMGYNFSLLGLLGEIIYIVLLVLDTV
GAGNGMIGFQVLLSIGELSLAIVIALMSGLLTGLLLNLK
IWKAPHEAKYFDDQVFWKFPHLAVGF
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_001121163.1
ncbi gb acc num :
NM_001127691.1
ncbi mol weight :
45,211 Da
ncbi summary :
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
RHD: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 1p36.11. Cellular Component: integral to plasma membrane. Molecular Function: ammonium transmembrane transporter activity