Recombinant Human Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) | MyBioSource MBS960691 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2)

catalog :

MBS960691

quantity :

0.5 mg (E-Coli)

price :

1095 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS960691

products type :

Recombinant Protein

products full name :

Recombinant Human Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2)

products short name :

Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2)

products name syn :

Eukaryotic translation initiation factor 2 subunit 2; Eukaryotic translation initiation factor 2 subunit beta; eIF-2-beta

other names :

eukaryotic translation initiation factor 2 subunit 2; Eukaryotic translation initiation factor 2 subunit 2; eukaryotic translation initiation factor 2 subunit 2; protein phosphatase 1, regulatory subunit 67; eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; Eukaryotic translation initiation factor 2 subunit beta; eIF-2-beta

products gene name :

EIF2S2

products gene name syn :

EIF2S2; EIF2B

other gene names :

EIF2S2; EIF2S2; EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta; EIF2B; eIF-2-beta

uniprot entry name :

IF2B_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-333

sequence length :

332

sequence :

SGDEMIFDP TMSKKKKKKK KPFMLDEEGD TQTEETQPSE TKEVEPEPTE DKDLEADEED TRKKDASDDL DDLNFFNQKK KKKKTKKIFD IDEAEEGVKD LKIESDVQEP TEPEDDLDIM LGNKKKKKKN VKFPDEDEIL EKDEALEDED NKKDDGISFS NQTGPAWAGS ERDYTYEELL NRVFNIMREK NPDMVAGEKR KFVMKPPQVV RVGTKKTSFV NFTDICKLLH RQPKHLLAFL LAELGTSGSI DGNNQLVIKG RFQQKQIENV LRRYIKEYVT CHTCRSPDTI LQKDTRLYFL QCETCHSRCS VASIKTGFQA VTGKRAQLRA KAN

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

ncbi gi num :

29826335

ncbi acc num :

NP_003899.2

ncbi gb acc num :

NM_003908.3

uniprot acc num :

P20042

ncbi mol weight :

38,388 Da

ncbi pathways :

Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (105970); BDNF Signaling Pathway (712093); Cap-dependent Translation Initiation Pathway (105967); Eukaryotic Translation Initiation Pathway (105966); Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway (105969); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (105973); Gene Expression Pathway (105937); L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway (160955); Metabolism Of Proteins Pathway (106230); RNA Transport Pathway (177876)

ncbi summary :

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. [provided by RefSeq, Jul 2008]

uniprot summary :

eIF2-beta: a translational regulatory protein that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. Protein type: Translation initiation; Translation. Chromosomal Location of Human Ortholog: 20q11.2. Cellular Component: cytoplasm; cytosol; nucleus; eukaryotic translation initiation factor 2 complex. Molecular Function: protein binding; RNA binding; translation factor activity, nucleic acid binding; translation initiation factor activity; metal ion binding. Biological Process: cellular protein metabolic process; translation; in utero embryonic development; male gonad development; translational initiation; gene expression

size1 :

0.5 mg (E-Coli)

price1 :

1095 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1095

size3 :

0.5 mg (Yeast)

price3 :

1325

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1325

size5 :

1 mg (E-Coli)

price5 :

1725

more info or order :

MyBioSource product webpage