catalog number :
MBS9606160
products full name :
IL13RA2 Antibody
products short name :
[IL13RA2]
products name syn :
[Cancer/testis antigen 19; CD213a2; CT19; I13R2_HUMAN; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; IL13 receptor; IL13BP; IL13R; Il13ra2; Interleukin 13 binding protein; Interleukin 13 receptor alpha 2 chain; Interleukin-13 receptor subunit alpha-2; Interleukin-13-binding protein]
other names :
[interleukin-13 receptor subunit alpha-2; Interleukin-13 receptor subunit alpha-2; interleukin-13 receptor subunit alpha-2; interleukin 13 receptor subunit alpha 2; Interleukin-13-binding protein; CD_antigen: CD213a2]
products gene name :
[IL13RA2]
other gene names :
[IL13RA2; IL13RA2; CT19; IL-13R; IL13BP; CD213A2; IL13R; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2]
reactivity :
Human, Mouse, Rat
specificity :
IL13RA2 antibody detects endogenous levels of total IL13RA2
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
form :
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:1000. IF/ICC: 1:100-1:500
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: A synthesized peptide. Subcellular Location: Membrane. . Similarity: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation.Belongs to the type I cytokine receptor family. Type 5 subfamily.
other info2 :
Conjugation: Unconjugated
products description :
Function: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). Similarity: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation. Belongs to the type I cytokine receptor family. Type 5 subfamily.
ncbi acc num :
NP_000631.1
ncbi gb acc num :
NM_000640.2
ncbi pathways :
IL4-mediated Signaling Events Pathway (137933); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)
ncbi summary :
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
uniprot summary :
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).