catalog number :
MBS9605876
products full name :
ALDH1A2 Antibody
products short name :
[ALDH1A2]
products name syn :
[AL1A2_HUMAN; Aldehyde dehydrogenase family 1 member A2; ALDH1A2 aldehyde dehydrogenase 1 family, member A2; ALDH1A2; Aldh1a7; AV116159; MGC26444; RALDH 2; RALDH(II); Raldh1; RalDH2; RALDH2 T; Retinal dehydrogenase 2; Retinaldehyde dehydrogenase 2; Retinaldehyde specific dehydrogenase type 2; Retinaldehyde-specific dehydrogenase type 2]
other names :
[retinal dehydrogenase 2 isoform 4; Retinal dehydrogenase 2; retinal dehydrogenase 2; aldehyde dehydrogenase 1 family member A2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II)]
products gene name :
[ALDH1A2]
other gene names :
[ALDH1A2; ALDH1A2; RALDH2; RALDH2-T; RALDH(II); RALDH2; RALDH 2; RalDH2; RALDH(II)]
reactivity :
Human, Mouse, Rat
specificity :
ALDH1A2 antibody detects endogenous levels of total ALDH1A2
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
WB: 1:500-1:1000. IF/ICC: 1:100-1:500
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide. Subcellular Location: Cytoplasm. Predicted Cross Reactivity : Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus . Similarity: Pig (100%), Zebrafish (80%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (90%)
other info2 :
Conjugation: Unconjugated
products description :
Function: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). Subunit Structure: Homotetramer. Similarity: Belongs to the aldehyde dehydrogenase family.
ncbi acc num :
NP_001193826.1
ncbi gb acc num :
NM_001206897.1
ncbi pathways :
Retinol Metabolism Pathway (83020); Retinol Metabolism Pathway (406); Tryptophan Metabolism Pathway (198850); Vitamin A And Carotenoid Metabolism Pathway (198785); Retinoate Biosynthesis I Pathway (545452); Retinoate Biosynthesis I Pathway (545295)
ncbi summary :
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
uniprot summary :
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently ().