catalog number :
MBS9605266
products full name :
ABCA8 Antibody
products short name :
[ABCA8]
products name syn :
[ABCA 8; ATP binding cassette sub family A member 8; ATP binding cassette, sub family A (ABC1), member 8]
other names :
[ATP-binding cassette sub-family A member 8 isoform 1; ATP-binding cassette sub-family A member 8; ATP-binding cassette sub-family A member 8; ATP binding cassette subfamily A member 8]
products gene name :
[ABCA8]
other gene names :
[ABCA8; ABCA8; KIAA0822]
reactivity :
Human, Mouse
specificity :
ABCA8 antibody detects endogenous levels of total ABCA8
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:1000. IF/ICC: 1:100-1:500
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human ABCA8, corresponding to a region within the internal amino acids. Similarity: Belongs to the ABC transporter superfamily. ABCA family.
ncbi acc num :
NP_001275914.1
ncbi gb acc num :
NM_001288985.1
ncbi pathways :
ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (106573); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
uniprot summary :
ATP-dependent lipophilic drug transporter.