product summary
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company name :
MyBioSource
product type :
antibody
product name :
SGCA Antibody
catalog :
MBS9605220
quantity :
0.1 mL
price :
240 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MBS9605220 staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(DF3764 1:200) and mouse anti-beta tubulin Ab(T0023 1:200) for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody.
image 2 :
Western blot analysis of extracts from mouse brian, using SGCA antibody.
product information
catalog number :
MBS9605220
products type :
Antibody
products full name :
SGCA Antibody
products short name :
[SGCA]
products name syn :
[50 DAG; 50 kDa dystrophin associated glycoprotein; 50 kDa dystrophin-associated glycoprotein; 50DAG; 50kD DAG; 59kDa; A2; adhalin; ADL; Alpha SG; Alpha-sarcoglycan; Alpha-SG; Asg; DAG2; DMDA2; Dystroglycan 2; Dystroglycan-2; LGMD2D; sarcoglycan, alpha (dystrophin-associated glycoprotein); SCARMD1; Sgca; SGCA_HUMAN]
other names :
[alpha-sarcoglycan isoform 1; Alpha-sarcoglycan; alpha-sarcoglycan; sarcoglycan alpha; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2]
products gene name :
[SGCA]
other gene names :
[SGCA; SGCA; ADL; DAG2; 50DAG; DMDA2; LGMD2D; LGMDR3; SCARMD1; adhalin; ADL; DAG2; Alpha-SG; 50DAG]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
specificity :
SGCA antibody detects endogenous levels of total SGCA
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:1000. IF/ICC: 1:100-1:500. IMPORTANT: For western blots, incubate membrane with diluted antibody in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.
image1 heading :
Immunofluorescence/Immunocytochemistry (IF/ICC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human SGCA, corresponding to a region within the internal amino acids.
products description :
Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Similarity: Belongs to the sarcoglycan alpha/epsilon family.
ncbi gi num :
4506911
ncbi acc num :
NP_000014.1
ncbi gb acc num :
NM_000023.3
uniprot acc num :
Q16586
ncbi mol weight :
43 KD
ncbi pathways :
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Viral Myocarditis Pathway (125138)
ncbi summary :
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
uniprot summary :
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
size1 :
0.1 mL
price1 :
240 USD
size2 :
0.2 mL
price2 :
280
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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