catalog number :
MBS9604996
products full name :
TMEM30B Antibody
products short name :
[TMEM30B]
products name syn :
[9130011B11Rik; CC50B_HUMAN; CDC50, S. cerevisiae, homolog of, B; CDC50B; Cell cycle control protein 50B; MGC126775; TMEM30B; Transmembrane protein 30B]
other names :
[cell cycle control protein 50B; Cell cycle control protein 50B; cell cycle control protein 50B; transmembrane protein 30B; P4-ATPase flippase complex beta subunit TMEM30B; Transmembrane protein 30B]
products gene name :
[TMEM30B]
other gene names :
[TMEM30B; TMEM30B; CDC50B; CDC50B]
reactivity :
Human, Mouse
specificity :
TMEM30B antibody detects endogenous levels of total TMEM30B
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Liquid. Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:1000. IF/ICC: 1:100-1:500
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human TMEM30B, corresponding to a region within the internal amino acids. Similarity: Belongs to the CDC50/LEM3 Family.
other info2 :
Important: For Western Blot (WB), incubate membrane with diluted Ab in 5% w/v milk, 1X TBS, 0.1% Tween(R)20 at 4 degree C with gentle shaking, overnight.
products description :
Function: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. Subunit Structure: Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit and an accessory beta subunit (Probable). Interacts with alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4. Similarity: Belongs to the CDC50/LEM3 family.
ncbi acc num :
NP_001017970.1
ncbi gb acc num :
NM_001017970.2
uniprot summary :
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.