product summary
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company name :
MyBioSource
product type :
antibody
product name :
URAT1 Antibody
catalog :
MBS9603568
quantity :
0.1 mL
price :
240 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
MBS9603568 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
image 2 :
Western blot analysis of extracts of PC-13 cells, using URAT1 antibody.
product information
catalog number :
MBS9603568
products type :
Antibody
products full name :
URAT1 Antibody
products short name :
[URAT1]
products name syn :
[Organic anion transporter 4-like protein; Renal-specific transporter; RST; S22AC_HUMAN; Slc22a12; Solute carrier family 22 member 12; Urate anion exchanger 1]
other names :
[solute carrier family 22 member 12 isoform c; Solute carrier family 22 member 12; solute carrier family 22 member 12; solute carrier family 22 member 12; Organic anion transporter 4-like protein; Renal-specific transporter; RST; Urate anion exchanger 1]
products gene name :
[URAT1]
products gene name syn :
[SLC22A12]
other gene names :
[SLC22A12; SLC22A12; RST; OAT4L; URAT1; OATL4; URAT1; RST]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Pig
sequence length :
519
specificity :
URAT1 Ab antibody detects endogenous levels of URAT1.
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
form :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human URAT1. Subcellular Location: Cell Membrane. Detected in the luminal membrane of the epithelium of renal proximal tubules. Tissue Specificity: Detected in kidney (at protein level). Detected in fetal and adult kidney. Detected in epithelial cells of proximal tubules in renal cortex. Predicted Cross Reactivity : Pig, Horse . Similarity: Pig (82%), Horse (91%)
other info2 :
Conjugation: Unconjugated
products description :
Function: Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions. Subunit Structure: Interacts with PDZK1. Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
ncbi gi num :
444299636
ncbi acc num :
NP_001263255.1
ncbi gb acc num :
NM_001276326.1
uniprot acc num :
Q96S37
ncbi mol weight :
65-70 kDa; 40 kDa
ncbi pathways :
Organic Anion Transport Pathway (1269938); Organic Cation/anion/zwitterion Transport Pathway (1269936); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1269923)
ncbi summary :
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
uniprot summary :
Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions.
size1 :
0.1 mL
price1 :
240 USD
size2 :
0.2 mL
price2 :
280
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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