Recombinant Rat Calcitonin gene-related peptide 1 (Calca) | MyBioSource MBS960353 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Rat Calcitonin gene-related peptide 1 (Calca)

catalog :

MBS960353

quantity :

1 mg (E-Coli)

price :

1375 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS960353

products type :

Recombinant Protein

products full name :

Recombinant Rat Calcitonin gene-related peptide 1 (Calca)

products short name :

Calcitonin gene-related peptide 1 (Calca)

products name syn :

Recombinant Calcitonin gene-related peptide 1 (Calca); Calcitonin gene-related peptide 1; Alpha-type CGRP Calcitonin gene-related peptide I; CGRP-I

other names :

calcitonin gene-related peptide 1 isoform Cgrp preproprotein; Calcitonin gene-related peptide 1; calcitonin gene-related peptide 1; CGRP-I; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; calcitonin-related polypeptide alpha; Alpha-type CGRP; Calcitonin gene-related peptide I

products gene name syn :

Calca; Calc

other gene names :

Calca; Calca; CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin; Calc; CGRP-I

uniprot entry name :

CALCA_RAT

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

other info1 :

Species: Rattus norvegicus (Rat)

ncbi gi num :

76880482

ncbi acc num :

NP_001029127.1

ncbi gb acc num :

NM_001033955.1

uniprot acc num :

P01256

ncbi mol weight :

13,948 Da

ncbi pathways :

Amyloids Pathway (649745); Calcitonin-like Ligand Receptors Pathway (648926); Class B/2 (Secretin Family Receptors) Pathway (648925); Disease Pathway (649740); GPCR Ligand Binding Pathway (648900); Myometrial Relaxation And Contraction Pathways (198465); Signal Transduction Pathway (648750); Signaling By GPCR Pathway (648899)

ncbi summary :

an inhibitor of lactotroph function and a potent vasodilator [RGD, Feb 2006]

uniprot summary :

CALCA iso3: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular space; neuron projection; cell soma; cell; axon; cytoplasm; extracellular region; terminal button; intracellular; nucleus. Molecular Function: neuropeptide hormone activity; identical protein binding; calcitonin receptor binding; protein complex binding; receptor binding. Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of cell adhesion; positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; protein amino acid phosphorylation; vasodilation; G-protein signaling, adenylate cyclase activating pathway; regulation of heart contraction; positive regulation of interleukin-8 production; monocyte chemotaxis; leukocyte adhesion; elevation of cytosolic calcium ion concentration; vasculature development; neuropeptide signaling pathway; negative regulation of smooth muscle contraction; regulation of blood pressure; receptor internalization; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; positive regulation of adenylate cyclase activity; negative regulation of blood pressure; negative regulation of bone resorption; inflammatory response; detection of temperature stimulus involved in sensory perception of pain; positive regulation of macrophage differentiation; negative regulation of neurological process; neuromuscular junction development; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; cellular calcium ion homeostasis; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation

size1 :

1 mg (E-Coli)

price1 :

1375 USD

size2 :

1 mg (Yeast)

price2 :

1835

more info or order :

MyBioSource product webpage