product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2)
catalog :
MBS960175
quantity :
1 mg (E Coli Derived
price :
2230 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS960175
products type :
Recombinant Protein
products full name :
Recombinant Human Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2)
products short name :
Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2)
other names :
interferon-induced, double-stranded RNA-activated protein kinase isoform a; Interferon-induced, double-stranded RNA-activated protein kinase; interferon-induced, double-stranded RNA-activated protein kinase; p68 kinase; eIF-2A protein kinase 2; P1/eIF-2A protein kinase; tyrosine-protein kinase EIF2AK2; interferon-inducible elF2alpha kinase; double stranded RNA activated protein kinase; protein phosphatase 1, regulatory subunit 83; protein kinase, interferon-inducible double stranded RNA dependent; eukaryotic translation initiation factor 2-alpha kinase 2; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein kinase; Protein kinase RNA-activated; PKR; Tyrosine-protein kinase EIF2AK2 (EC:2.7.10.2); p68 kinase
products gene name :
EIF2AK2
other gene names :
EIF2AK2; EIF2AK2; PKR; PRKR; EIF2AK1; PPP1R83; PKR; PRKR; eIF-2A protein kinase 2; PKR
uniprot entry name :
E2AK2_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-551
sequence length :
551
sequence :
AGDLSAGFF MEELNTYRQK QGVVLKYQEL PNSGPPHDRR FTFQVIIDGR EFPEGEGRSK KEAKNAAAKL AVEILNKEKK AVSPLLLTTT NSSEGLSMGN YIGLINRIAQ KKRLTVNYEQ CASGVHGPEG FHYKCKMGQK EYSIGTGSTK QEAKQLAAKL AYLQILSEET SVKSDYLSSG SFATTCESQS NSLVTSTLAS ESSSEGDFSA DTSEINSNSD SLNSSSLLMN GLRNNQRKAK RSLAPRFDLP DMKETKYTVD KRFGMDFKEI ELIGSGGFGQ VFKAKHRIDG KTYVIKRVKY NNEKAEREVK ALAKLDHVNI VHYNGCWDGF DYDPETSDDS LESSDYDPEN SKNSSRSKTK CLFIQMEFCD KGTLEQWIEK RRGEKLDKVL ALELFEQITK GVDYIHSKKL IHRDLKPSNI FLVDTKQVKI GDFGLVTSLK NDGKRTRSKG TLRYMSPEQI SSQDYGKEVD LYALGLILAE LLHVCDTAFE TSKFFTDLRD GIISDIFDKK EKTLLQKLLS KKPEDRPNTS EILRTLTVWK KSPEKNERHT C
purity :
>90%
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
products description :
EIF2AK2; PKR, PRKR
ncbi gi num :
208431827
ncbi acc num :
NP_001129123.1
ncbi gb acc num :
NM_001135651.2
uniprot acc num :
P19525
ncbi mol weight :
57,391 Da
ncbi pathways :
Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Ceramide Signaling Pathway 138023!!Cytokine Signaling In Immune System Pathway 366171!!Disease Pathway 530764!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!Hepatitis C Pathway 173973!!Hepatitis C Pathway 173907!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865
ncbi summary :
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
size :
1 mg (E Coli Derived)
price :
2230 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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