Recombinant Human Casein kinase II subunit beta (CSNK2B) | MyBioSource MBS960149 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Casein kinase II subunit beta (CSNK2B)

catalog :

MBS960149

quantity :

0.5 mg (E-Coli)

price :

965 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS960149

products type :

Recombinant Protein

products full name :

Recombinant Human Casein kinase II subunit beta (CSNK2B)

products short name :

Casein kinase II subunit beta (CSNK2B)

products name syn :

Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a

other names :

casein kinase II subunit beta isoform 2; Casein kinase II subunit beta; casein kinase II subunit beta; phosvitin; CK II beta; protein G5a; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; Casein kinase II beta subunit; alternative name: G5a, phosvitin; chimera CSNK2B-LY6G5B splicing isoform 532; chimera CSNK2B-LY6G5B splicing isoform 560; casein kinase II b subunit splicing isoform 318; casein kinase II b subunit splicing isoform 660; casein kinase II b subunit splicing isoform 806; casein kinase 2, beta polypeptide; Phosvitin; Protein G5a

products gene name :

CSNK2B

products gene name syn :

CSNK2B; CK2N; G5A

other gene names :

CSNK2B; CSNK2B; G5A; CK2B; CK2N; CSK2B; CK2N; G5A; CK II beta

uniprot entry name :

CSK2B_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-215

sequence length :

214

sequence :

SSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

products description :

Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.

ncbi gi num :

538260597

ncbi acc num :

NP_001269314.1

ncbi gb acc num :

NM_001282385.1

uniprot acc num :

P67870

ncbi mol weight :

50kD

ncbi pathways :

ALK1 Signaling Events Pathway (137968); Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Axon Guidance Pathway (105688); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Condensation Of Prometaphase Chromosomes Pathway (730316); Developmental Biology Pathway (477129); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115)

ncbi summary :

This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

uniprot summary :

CK2B: a regulatory subunit of the casein kinase 2 holoenzyme. Exists as a tetramer composed of two catalytic subunits, alpha and alpha-prime, and two regulatory beta subunits. The beta subunits undergo autophosphorylation. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Participates in Wnt signaling. Protein type: Protein kinase, regulatory subunit. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: cytoplasm; plasma membrane; protein kinase CK2 complex; PcG protein complex; cytosol; nucleus. Molecular Function: identical protein binding; protein serine/threonine kinase activity; protein domain specific binding; protein binding; metal ion binding; protein kinase regulator activity; transcription factor binding; receptor binding. Biological Process: negative regulation of cell proliferation; axon guidance; positive regulation of activin receptor signaling pathway; Wnt receptor signaling pathway; cellular protein complex assembly; regulation of DNA binding; adiponectin-mediated signaling pathway; mitotic cell cycle; signal transduction; regulation of protein kinase activity; negative regulation of blood vessel endothelial cell migration; protein amino acid phosphorylation

size1 :

0.5 mg (E-Coli)

price1 :

965 USD

size2 :

0.05 mg (Baculovirus)

price2 :

965

size3 :

0.5 mg (Yeast)

price3 :

1190

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1190

size5 :

1 mg (E-Coli)

price5 :

1450

more info or order :

MyBioSource product webpage