product summary
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company name :
MyBioSource
product type :
antibody
product name :
ZEB2 Antibody
catalog :
MBS9601451
quantity :
0.1 mL
price :
240 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MBS9601451 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
image 2 :
MBS9601451 at 1/100 staining human liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
image 3 :
Western blot analysis of ZEB2 expression in HepG2 cell lysate, The lane on the left is treated with the antigen-specific peptide.
product information
catalog number :
MBS9601451
products type :
Antibody
products full name :
ZEB2 Antibody
products short name :
[ZEB2]
products name syn :
[FLJ42816; HSPC082; KIAA0569; SIP 1; SIP1; Smad-interacting protein 1; SMADIP 1; SMADIP1; ZEB 2; Zeb2; ZEB2_HUMAN; Zfhx1b; ZFHX1B protein; Zfx1b; Zinc finger E box binding protein 2; Zinc finger E-box-binding homeobox 2; Zinc finger homeobox 1b; zinc finger homeobox protein 1; Zinc finger homeobox protein 1b]
other names :
[zinc finger E-box-binding homeobox 2 isoform 2; Zinc finger E-box-binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger E-box binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b]
products gene name :
[ZEB2]
other gene names :
[ZEB2; ZEB2; SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; KIAA0569; SIP1; ZFHX1B; ZFX1B; SMADIP1]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
1190
specificity :
ZEB2 antibody detects endogenous levels of total ZEB2
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200. IF/ICC: 1:100-1:500
image1 heading :
Immunofluorescence (IF)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human ZEB2 corresponding to a region within N-terminal amino acids.
products description :
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Similarity: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
products references :
YaoduWang, ZhiyangWu, LikuanHu; Journal: EUR J PHARMACOL. The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
ncbi gi num :
284413746
ncbi acc num :
NP_001165124.1
ncbi gb acc num :
NM_001171653.1
uniprot acc num :
O60315
ncbi mol weight :
136 kDa
ncbi pathways :
TGF Beta Signaling Pathway (198810); TGF-beta Receptor Signaling Pathway (198774)
ncbi summary :
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
uniprot summary :
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.
size1 :
0.1 mL
price1 :
240 USD
size2 :
0.2 mL
price2 :
280
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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