catalog number :
MBS9600194
products full name :
Synaptophysin Antibody
products short name :
[Synaptophysin]
products name syn :
[Major synaptic vesicle protein p38; MRX96; MRXSYP; Syn p38; Synaptophysin; Syp; SYPH; SYPH_HUMAN; SypI]
other names :
[synaptophysin; Synaptophysin; synaptophysin; synaptophysin; Major synaptic vesicle protein p38]
products gene name :
[SYP]
other gene names :
[SYP; SYP; MRX96; MRXSYP]
reactivity :
Human, Mouse, Rat
specificity :
Synaptophysin antibody detects endogenous levels of total Synaptophysin
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
form :
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
app notes :
WB: 1:500-1:3000. IHC: 1:50-1:200. IF: 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: A synthesized peptide derived from human Synaptophysin, corresponding to a region within the internal amino acids.
products description :
Description: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Belongs to the synaptophysin/synaptobrevin family. Homohexamer or homotetramer. Note: This description may include information from UniProtKB. Similarity: The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein. Belongs to the synaptophysin/synaptobrevin family.
ncbi acc num :
NP_003170.1
ncbi gb acc num :
NM_003179.2
ncbi pathways :
Synaptic Vesicle Pathway (672457)
ncbi summary :
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]
uniprot summary :
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity ().