catalog number :
MBS959988
products type :
Recombinant Protein
products full name :
Recombinant human Mucin-1 protein,partial
products short name :
Mucin-1 protein,partial
other names :
mucin-1 isoform 2; Mucin-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-betaAlternative name(s):MUC1-CT
products gene name :
MUC1
other gene names :
MUC1; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta
uniprot entry name :
MUC1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
24-273
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Species: Human
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
products description :
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
ncbi acc num :
NP_001018016.1
ncbi gb acc num :
NM_001018016.2
ncbi mol weight :
28,297 Da
ncbi pathways :
IL-7 Signaling Pathway 198857!!Metabolism Of Proteins Pathway 106230!!O-linked Glycosylation Of Mucins Pathway 530747!!Post-translational Protein Modification Pathway 161012!!Termination Of O-glycan Biosynthesis Pathway 530748
size :
1 mg (E Coli Derived)