product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Nuclear receptor ROR-beta (Rorb)
catalog :
MBS959495
quantity :
0.5 mg (E-Coli)
price :
1250 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS959495
products type :
Recombinant Protein
products full name :
Recombinant Rat Nuclear receptor ROR-beta (Rorb)
products short name :
Nuclear receptor ROR-beta (Rorb)
products name syn :
Nuclear receptor ROR-beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; Retinoid-related orphan receptor-beta
other names :
Nuclear receptor ROR-beta; Nuclear receptor ROR-beta; nuclear receptor ROR-beta; transcription factor; nuclear receptor RZR-beta; RAR-related orphan receptor beta; retinoid-related orphan receptor-beta; nuclear receptor subfamily 1 group F member 2; RAR-related orphan receptor B; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; Retinoid-related orphan receptor-beta
products gene name :
Rorb
products gene name syn :
Rorb; Nr1f2; Rzrb
other gene names :
Rorb; Rorb; Nr1f2; Rzrb
uniprot entry name :
RORB_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-470
sequence length :
470
sequence :
MCENQLKTKA DGTAQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQQ NNASYSCPRQ RNCLIDRTNR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLYAEVQK HQQRLQEQRQ QQSGEAEALA RVYSSSISNG LSNLNTETGG TYANGHVIDL PKSEGYYNID SGQPSPDQSG LDMTGIKQIK QEPIYDLTSV HNLFTYSSFN NGQLAPGITM SEIDRIAQNI IKSHLETCQY TMEELHQLAW QTHTYEEIKA YQSKSREALW QQCAIQITHA IQYVVEFAKR ITGFMELCQN DQILLLKSGC LEVVLVRMCR AFNPLNNTVL FEGKYGGMQM FKALGSDDLV NEAFDFAKNL CSLQLTEEEI ALFSSAVLIS PDRAWLLEPR KVQKLQEKIY FALQHVIQKN HLDDETLAKL IAKIPTITAV CNLHGEKLQV FKQSHPDIVN TLFPPLYKEL FNPDCAAVCK
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rattus norvegicus (Rat)
ncbi gi num :
124028632
ncbi acc num :
P45446.3
uniprot acc num :
P45446
ncbi mol weight :
52,068 Da
ncbi pathways :
Circadian Rhythm Pathway (83476); Circadian Rhythm Pathway (495); Gene Expression Pathway (1010398); Generic Transcription Pathway (1010399); Nuclear Receptor Transcription Pathway (1010401)
ncbi summary :
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
uniprot summary :
RORB: Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5 -AGGTCA-3 in the OPN1SW promoter. Belongs to the nuclear hormone receptor family. NR1 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: DNA-binding; Nuclear receptor. Cellular Component: nucleus. Molecular Function: ligand-dependent nuclear receptor activity; zinc ion binding; sequence-specific DNA binding; melatonin receptor activity; steroid hormone receptor activity; transcription factor activity; transcription factor binding. Biological Process: circadian rhythm; intracellular receptor-mediated signaling pathway; retinal rod cell development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; response to hormone stimulus; regulation of circadian rhythm; G-protein coupled receptor protein signaling pathway; eye photoreceptor cell development; visual perception; retinal cone cell development; retina development in camera-type eye; negative regulation of osteoblast differentiation; steroid hormone mediated signaling; brain development; negative regulation of transcription, DNA-dependent
size1 :
0.5 mg (E-Coli)
price1 :
1250 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1250
size3 :
0.5 mg (Yeast)
price3 :
1470
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1470
size5 :
1 mg (E-Coli)
price5 :
2045
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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