catalog number :
MBS958874
products type :
Recombinant Protein
products full name :
Recombinant Rat Matrilysin
products short name :
Matrilysin
products name syn :
Matrin; Matrix metalloproteinase-7; MMP-7Pump-1 protease; Uterine metalloproteinase
other names :
matrilysin; Matrilysin; matrilysin; matrix metallopeptidase 7; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase
products gene name :
Mmp7
other gene names :
Mmp7; Mmp7; MPMM; Mmp-7; MMP-7
uniprot entry name :
MMP7_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
98-267
sequence :
FSLMPNSPKWHSRTVTYRIVSYTTDLPRFLVDQIVKRAL
RMWSMQIPLNFKRVSWGTADIIIGFARGDHGDNFPFDGP
GNTLGHAFAPGPGLGGDAHFDKDEYWTDGEDSGVNFLFV
ATHELGHSLGLGHSSVPSSVMYPTYQGDHSEDFSLTKDD
IAGIQKLYGKRNKL
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
products references :
Characterization of rat uterine matrilysin and its cDNA. Relationship to human pump-1 and activation of procollagenases.Abramson S.R., Conner G.E., Nagase H., Neuhaus I., Woessner J.F.J. Biol. Chem. 270:16016-16022(1995)
ncbi acc num :
NP_036996.1
ncbi gb acc num :
NM_012864.2
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (1332751); Alpha6-Beta4 Integrin Signaling Pathway (198503); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (1332740); Collagen Degradation Pathway (1332752); Collagen Formation Pathway (1332738); Degradation Of The Extracellular Matrix Pathway (1332750); Extracellular Matrix Organization Pathway (1332737); Matrix Metalloproteinases Pathway (198492); Wnt Signaling Pathway And Pluripotency (219793); Wnt Signaling Pathway (83453)
ncbi summary :
enzyme that cleaves the alpha 2(I) chain of rat gelatin [RGD, Feb 2006]