catalog number :
MBS958374
products type :
Recombinant Protein
products full name :
Recombinant Human Acyloxyacyl hydrolase (AOAH)
products short name :
Acyloxyacyl hydrolase (AOAH)
products name syn :
Acyloxyacyl hydrolase; EC=3.1.1.77Cleaved into the following 2 chains:; 1. Acyloxyacyl hydrolase small subunit; 2. Acyloxyacyl hydrolase large subunit
other names :
acyloxyacyl hydrolase isoform 2 preproprotein; Acyloxyacyl hydrolase; acyloxyacyl hydrolase; acyloxyacyl hydrolase (neutrophil)
products gene name :
AOAH
other gene names :
AOAH; AOAH
uniprot entry name :
AOAH_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
35-156
sequence :
LSNGHT CVGCVLVVSV IEQLAQVHNS TVQASMERLC SYLPEKLFLK TTCYLVIDKF GSDIIKLLSA DMNADVVCHT LEFCKQNTGQ PLCHLYPLPK ETWKFTLQKA RQIVKKSPIL KYSRSG
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_001170977.1
ncbi gb acc num :
NM_001177506.1
ncbi mol weight :
61,647 Da
ncbi summary :
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
uniprot summary :
AOAH: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; EC 3.1.1.77; Secreted; Lipase. Chromosomal Location of Human Ortholog: 7p14.2. Cellular Component: extracellular region. Molecular Function: lipoprotein lipase activity; acyloxyacyl hydrolase activity; catalytic activity. Biological Process: lipid metabolic process; inflammatory response
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)