catalog number :
MBS958359
products type :
Recombinant Protein
products full name :
Recombinant Human Chymotrypsin-like elastase family member 3B (CELA3B)
products short name :
Chymotrypsin-like elastase family member 3B(CELA3B)
other names :
chymotrypsin-like elastase family member 3B preproprotein; Chymotrypsin-like elastase family member 3B; chymotrypsin-like elastase family member 3B; elastase 1; protease E; elastase-3B; proteinase E; elastase IIIB; fecal elastase 1; pancreatic elastase 1; elastase 3B, pancreatic; pancreatic endopeptidase E; cholesterol-binding pancreatic protease; chymotrypsin-like elastase family, member 3B; Elastase IIIB; Elastase-3B; Protease E
products gene name :
CELA3B
other gene names :
CELA3B; CELA3B; E1; CBPP; EL-1; ELA3B; ELA3B
uniprot entry name :
CEL3B_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
29-270
sequence :
VV NGEDAVPYSW PWQVSLQYEK SGSFYHTCGG SLIAPDWVVT AGHCISSSRT YQVVLGEYDR AVKEGPEQVI PINSGDLFVH PLWNRSCVAC GNDIALIKLS RSAQLGDAVQ LASLPPAGDI LPNETPCYIT GWGRLYTNGP LPDKLQEALL PVVDYEHCSR WNWWGSSVKK TMVCAGGDIR SGCNGDSGGP LNCPTEDGGW QVHGVTSFVS AFGCNTRRKP TVFTRVSAFI DWIEETIASH
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_031378.1
ncbi gb acc num :
NM_007352.2
ncbi mol weight :
29,263 Da
ncbi pathways :
Pancreatic Secretion Pathway 169306!!Pancreatic Secretion Pathway 169295!!Protein Digestion And Absorption Pathway 172847!!Protein Digestion And Absorption Pathway 171868
ncbi summary :
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009]
size :
1 mg (E Coli Derived)