Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) | MyBioSource MBS957287 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3)

catalog :

MBS957287

quantity :

0.5 mg (E-Coli)

price :

1255 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS957287

products type :

Recombinant Protein

products full name :

Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3)

products short name :

Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3)

products name syn :

Eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initiation factor 2 subunit gamma X; eIF-2-gamma X; eIF-2gX

other names :

eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initiation factor 2 subunit 3; eukaryotic translation initiation factor 2 subunit 3; eIF-2gX; eIF-2-gamma X; eukaryotic translation initiation factor 2G; eukaryotic translation initiation factor 2 subunit gamma X; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; Eukaryotic translation initiation factor 2 subunit gamma X; eIF-2-gamma X; eIF-2gX

products gene name :

EIF2S3

products gene name syn :

EIF2S3; EIF2G

other gene names :

EIF2S3; EIF2S3; EIF2; EIF2G; eIF-2gA; EIF2gamma; EIF2G; eIF-2-gamma X; eIF-2gX

uniprot entry name :

IF2G_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-472

sequence length :

471

sequence :

AGGEAGVTL GQPHLSRQDL TTLDVTKLTP LSHEVISRQA TINIGTIGHV AHGKSTVVKA ISGVHTVRFK NELERNITIK LGYANAKIYK LDDPSCPRPE CYRSCGSSTP DEFPTDIPGT KGNFKLVRHV SFVDCPGHDI LMATMLNGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM KLKHILILQN KIDLVKESQA KEQYEQILAF VQGTVAEGAP IIPISAQLKY NIEVVCEYIV KKIPVPPRDF TSEPRLIVIR SFDVNKPGCE VDDLKGGVAG GSILKGVLKV GQEIEVRPGI VSKDSEGKLM CKPIFSKIVS LFAEHNDLQY AAPGGLIGVG TKIDPTLCRA DRMVGQVLGA VGALPEIFTE LEISYFLLRR LLGVRTEGDK KAAKVQKLSK NEVLMVNIGS LSTGGRVSAV KADLGKIVLT NPVCTEVGEK IALSRRVEKH WRLIGWGQIR RGVTIKPTVD DD

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

ncbi gi num :

4503507

ncbi acc num :

NP_001406.1

ncbi gb acc num :

NM_001415.3

uniprot acc num :

P41091

ncbi mol weight :

51,109 Da

ncbi pathways :

Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (105970); Cap-dependent Translation Initiation Pathway (105967); Eukaryotic Translation Initiation Pathway (105966); Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway (105969); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (105973); Gene Expression Pathway (105937); L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway (160955); Metabolism Of Proteins Pathway (106230); RNA Transport Pathway (177876); RNA Transport Pathway (175229)

ncbi summary :

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

uniprot summary :

eIF2-gamma: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. Protein type: Translation initiation; Translation. Chromosomal Location of Human Ortholog: Xp22.2-p22.1. Cellular Component: cytoplasm; nucleus; cytosol. Molecular Function: GTPase activity; protein binding; GTP binding; translation factor activity, nucleic acid binding; translation initiation factor activity. Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression

size1 :

0.5 mg (E-Coli)

price1 :

1255 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1255

size3 :

0.5 mg (Yeast)

price3 :

1475

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1475

size5 :

1 mg (E-Coli)

price5 :

2045

more info or order :

MyBioSource product webpage