protein

Recombinant Human 14-3-3 protein epsilon (YWHAE)

MBS957003

0.5 mg (E-Coli)

1005 USD

Recombinant Protein

Recombinant Human 14-3-3 protein epsilon (YWHAE)

14-3-3 protein epsilon (YWHAE)

14-3-3 protein epsilon; 14-3-3E

14-3-3 protein epsilon; 14-3-3 protein epsilon; 14-3-3 protein epsilon; 14-3-3 epsilon; epididymis luminal protein 2; protein kinase C inhibitor protein-1; mitochondrial import stimulation factor L subunit; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

YWHAE

YWHAE; YWHAE; MDS; HEL2; MDCR; KCIP-1; 14-3-3E; 14-3-3E

1433E_HUMAN

E Coli or Yeast or Baculovirus or Mammalian Cell

1-255

255

MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE EQNKEALQDV EDENQ

>90%

Liquid containing glycerol; lyophilization may be available upon request.

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Species: Homo sapiens (Human)

5803225

NP_006752.1

NM_006761.4

P62258

26,504 Da

Activation Of BAD And Translocation To Mitochondria Pathway (105659); Activation Of BH3-only Proteins Pathway (105658); Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (105648); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463)

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

14-3-3 epsilon: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 17p13.3. Cellular Component: kinesin complex; focal adhesion; cytoplasmic vesicle membrane; mitochondrion; membrane; axon; melanosome; cytosol. Molecular Function: protein domain specific binding; protein binding; enzyme binding; potassium channel regulator activity; protein heterodimerization activity; histone deacetylase binding; phosphoprotein binding; phosphoserine binding. Biological Process: substantia nigra development; viral reproduction; nerve growth factor receptor signaling pathway; apoptosis; organelle organization and biogenesis; hippocampus development; neuron migration; cerebral cortex development; mitotic cell cycle; regulation of caspase activity; G2/M transition of mitotic cell cycle; regulation of the rate of heart contraction by hormone; protein targeting. Disease: Miller-dieker Lissencephaly Syndrome

0.5 mg (E-Coli)

1005 USD

0.05 mg (Baculovirus)

1005

0.5 mg (Yeast)

1235

0.05 mg (Mammalian-Cell)

1235

1 mg (E-Coli)

1545