catalog number :
MBS956471
products type :
Recombinant Protein
products full name :
Recombinant Rat Kelch-like ECH-associated protein 1 (Keap1)
products short name :
Kelch-like ECH-associated protein 1 (Keap1)
other names :
Kelch-like ECH-associated protein 1; Kelch-like ECH-associated protein 1; kelch-like ECH-associated protein 1; cytosolic inhibitor of Nrf2; Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2
products gene name :
Keap1
other gene names :
Keap1; Keap1; Inrf2; Inrf2; INrf2
uniprot entry name :
KEAP1_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-624
sequence :
MQPEPKPSGA PRSSQFLPLW SKCPEGAGDA VMYASTECKA EVTPSQDGNR TFSYTLEDHT KQAFGIMNEL RLSQQLCDVT LQVKYEDIPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM EVVSIEGIHP KVMERLIEFA YTASISVGEK CVLHVMNGAV MYQIDSVVRA CSDFLVQQLD PSNAIGIANF AEQIGCTELH QRAREYIYMH FGEVAKQEEF FNLSHCQLAT LISRDDLNVR CESEVFHACI DWVKYDCPQR RFYVQALLRA VRCHALTPRF LQTQLQKCEI LQADARCKDY LVQIFQELTL HKPTQAVPCR APKVGRLIYT AGGYFRQSLS YLEAYNPSNG SWLRLADLQV PRSGLAGCVV GGLLYAVGGR NNSPDGNTDS SALDCYNPMT NQWSPCASLS VPRNRSGGGV IDGHIYAVGG SHGCIHHSSV ERYEPDRDEW HLVAPMLTRR IGVGVAVLNR LLYAVGGFDG TNRLNSAECY YPERNEWRMI TPMNTIRSGA GVCVLHSCIY AAGGYDGQDQ LNSVERYDVE TETWTFVASM KHRRSALGIA VHQGRIYVLG GYDGHTFLDS VECYDPDTDT WSEVTRLTSG RSGVGVAVTM EPCRKQIDQQ NCTC
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Rattus norvegicus (Rat)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi mol weight :
69,399 Da
ncbi pathways :
Adaptive Immune System Pathway 1010925!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 1010943!!Class I MHC Mediated Antigen Processing Presentation Pathway 1010942!!Immune System Pathway 1010924!!Keap1-Nrf2 Pathway 219759!!NFE2L2 Pathway 739005!!Ubiquitin Mediated Proteolysis Pathway 83448!!Ubiquitin Mediated Proteolysis Pathway 466
ncbi summary :
binds nuclear transcription factor Nrf2 and retains it in the cytoplasm thus inhibiting it from functioning in the nucleus [RGD, Feb 2006]
size :
1 mg (E Coli Derived)