product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Macaca mulatta (Rhesus macaque) C-C chemokine receptor type 5 (CCR5)
catalog :
MBS956064
quantity :
1 mg (E-Coli)
price :
1725 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS956064
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) C-C chemokine receptor type 5 (CCR5)
products short name :
(Rhesus macaque) C-C chemokine receptor type 5 (CCR5)
products name syn :
Recombinant (Rhesus macaque) C-C chemokine receptor type 5 (CCR5); C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CD_antigen= CD195
other names :
C-C chemokine receptor type 5; C-C chemokine receptor type 5; C-C chemokine receptor type 5; CCR-5; CC-CKR-5; C-C CKR-5; CC chemokine receptor 5
products gene name syn :
CCR5; CMKBR5
other gene names :
CCR5; CCR5; CMKBR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5
uniprot entry name :
CCR5_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-352
sequence length :
352
sequence :
MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSL
VFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLL
FLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIF
FIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVA
VFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQT
LKMVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAV
RLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSN
RLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFF
QKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVG
L
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi gi num :
116812907
ncbi acc num :
NP_001036238.2
ncbi gb acc num :
NM_001042773.2
uniprot acc num :
P61813
ncbi mol weight :
40,507 Da
ncbi pathways :
Chemokine Signaling Pathway (99278); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (86721); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102291); Endocytosis Pathway (102181); Toxoplasmosis Pathway (169645); Toxoplasmosis Pathway (169493)
uniprot summary :
Function: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation . By similarity. Subunit structure: Interacts with PRAF2. Efficient ligand binding to CCL3/MIP-1alpha and CCL4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on Ser-6 is required for efficient binding of CCL4. Interacts with ADRBK1. Interacts with ARRB1 and ARRB2 . By similarity. Subcellular location: Cell membrane; Multi-pass membrane protein. Post-translational modification: Sulfated on at least 2 of the N-terminal tyrosines. Sulfation is required for efficient binding of the chemokines, CCL3 and CCL4 . By similarity.O-glycosylated, but not N-glycosylated. Ser-6 appears to be the major site. Also sialylated glycans present which contribute to chemokine binding. Thr-16 and Ser-17 may also be glycosylated and, if so, with small moieties such as a T-antigen . By similarity.Palmitoylation in the C-terminal is important for cell surface expression . By similarity.Phosphorylation on serine residues in the C-terminal is stimulated by binding CC chemokines especially by APO-RANTES . By similarity. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
size1 :
1 mg (E-Coli)
price1 :
1725 USD
size2 :
1 mg (Yeast)
price2 :
2180
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!