product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Neutrophil defensin 3 (DEFA3)
catalog :
MBS955711
quantity :
0.5 mg (E-Coli)
price :
780 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS955711
products type :
Recombinant Protein
products full name :
Recombinant Human Neutrophil defensin 3 (DEFA3)
products short name :
Neutrophil defensin 3 (DEFA3)
products name syn :
Neutrophil defensin 3; Defensin, alpha 3; HNP-3; HP-3; HP3Cleaved into the following 2 chains:; 1. HP 3-56; 2. Neutrophil defensin 2; HNP-2; HP-2; HP2
other names :
neutrophil defensin 3 preproprotein; Neutrophil defensin 3; neutrophil defensin 3; neutrophil peptide 3; defensin 3, neutrophil-specific; defensin, alpha 3, neutrophil-specific; Defensin, alpha 3; HNP-3; HP-3; HP3
products gene name :
DEFA3
products gene name syn :
DEFA3; DEF3
other gene names :
DEFA3; DEFA3; HP3; DEF3; HNP3; HP-3; HNP-3; DEF3; HP-3; HP3; HP-2; HP2
uniprot entry name :
DEF3_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
39-94
sequence length :
56
sequence :
DI PEVVVSLAWD ESLAPKHPGS RKNMDCYCRI PACIAGERRY GTCIYQGRLW AFCC
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
ncbi gi num :
4885179
ncbi acc num :
NP_005208.1
ncbi gb acc num :
NM_005217.3
uniprot acc num :
P59666
ncbi mol weight :
8kD
ncbi pathways :
Alpha-defensins Pathway (530758); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387); Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
ncbi summary :
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, May 2010]
uniprot summary :
defensin, alpha 3: Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Belongs to the alpha-defensin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8p23.1. Cellular Component: extracellular space; Golgi lumen; extracellular region. Biological Process: defense response to Gram-positive bacterium; estrogen receptor signaling pathway; innate immune response in mucosa; killing of cells of another organism; antibacterial humoral response; innate immune response; defense response to virus; defense response to fungus
size1 :
0.5 mg (E-Coli)
price1 :
780 USD
size2 :
0.05 mg (Baculovirus)
price2 :
780
size3 :
0.5 mg (Yeast)
price3 :
1005
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1005
size5 :
1 mg (E-Coli)
price5 :
1090
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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