catalog number :
MBS955098
products type :
Recombinant Protein
products full name :
Recombinant Rat Lysosome-associated membrane glycoprotein 2 (Lamp2)
products short name :
Lysosome-associated membrane glycoprotein 2 (Lamp2)
products name syn :
Recombinant Lysosome-associated membrane glycoprotein 2 (Lamp2); Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B LGP-110 LGP-96 Lysosomal membrane glycoprotein type B; LGP-B C
other names :
Lysosome-associated membrane glycoprotein 2; Lysosome-associated membrane glycoprotein 2; lysosome-associated membrane glycoprotein 2; LGP-B; LAMP-2; LGP-96; LGP-110; lysosomal membrane glycoprotein 2; CD107 antigen-like family member B; lysosomal membrane glycoprotein type B; lysosome-associated membrane protein 2; lysosomal-associated membrane protein 2; CD107 antigen-like family member B; LGP-110; LGP-96; Lysosomal membrane glycoprotein type B
products gene name syn :
Lamp2; Lamp-2
other gene names :
Lamp2; Lamp2; Lamp-2; LAMP-2; Lysosome-associated membrane protein 2; LGP-B
uniprot entry name :
LAMP2_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
26-376
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Rattus norvegicus (Rat)
ncbi mol weight :
45,164 Da
ncbi pathways :
Hemostasis Pathway (648959); Lysosome Pathway (98756); Lysosome Pathway (96865); Phagosome Pathway (153901); Phagosome Pathway (153859); Platelet Activation, Signaling And Aggregation Pathway (648969); Platelet Degranulation Pathway (648981); Response To Elevated Platelet Cytosolic Ca2+ Pathway (648979); Senescence And Autophagy Pathway (219773); Tuberculosis Pathway (213777)
ncbi summary :
intrinsic lysosomal membrane protein [RGD, Feb 2006]
uniprot summary :
Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane. Post-translational modification: O- and N-glycosylated; some of the N-glycans attached to Lamp-2 are polylactosaminoglycans . By similarity. Sequence similarities: Belongs to the LAMP family.