product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Leukotriene A-4 hydrolase (LTA4H)
catalog :
MBS955031
quantity :
0.5 mg (E-Coli)
price :
1405 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS955031
products type :
Recombinant Protein
products full name :
Recombinant Human Leukotriene A-4 hydrolase (LTA4H)
products short name :
Leukotriene A-4 hydrolase (LTA4H)
products name syn :
Leukotriene A-4 hydrolase; LTA-4 hydrolase; EC=3.3.2.6; Leukotriene A(4) hydrolase
other names :
leukotriene A-4 hydrolase isoform 1; Leukotriene A-4 hydrolase; leukotriene A-4 hydrolase; LTA-4 hydrolase; leukotriene A4 hydrolase; Leukotriene A(4) hydrolase
products gene name :
LTA4H
products gene name syn :
LTA4H; LTA4
other gene names :
LTA4H; LTA4H; LTA4; LTA-4 hydrolase
uniprot entry name :
LKHA4_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-611
sequence length :
610
sequence :
PEIVDTCSL ASPASVCRTK HLHLRCSVDF TRRTLTGTAA LTVQSQEDNL RSLVLDTKDL TIEKVVINGQ EVKYALGERQ SYKGSPMEIS LPIALSKNQE IVIEISFETS PKSSALQWLT PEQTSGKEHP YLFSQCQAIH CRAILPCQDT PSVKLTYTAE VSVPKELVAL MSAIRDGETP DPEDPSRKIY KFIQKVPIPC YLIALVVGAL ESRQIGPRTL VWSEKEQVEK SAYEFSETES MLKIAEDLGG PYVWGQYDLL VLPPSFPYGG MENPCLTFVT PTLLAGDKSL SNVIAHEISH SWTGNLVTNK TWDHFWLNEG HTVYLERHIC GRLFGEKFRH FNALGGWGEL QNSVKTFGET HPFTKLVVDL TDIDPDVAYS SVPYEKGFAL LFYLEQLLGG PEIFLGFLKA YVEKFSYKSI TTDDWKDFLY SYFKDKVDVL NQVDWNAWLY SPGLPPIKPN YDMTLTNACI ALSQRWITAK EDDLNSFNAT DLKDLSSHQL NEFLAQTLQR APLPLGHIKR MQEVYNFNAI NNSEIRFRWL RLCIQSKWED AIPLALKMAT EQGRMKFTRP LFKDLAAFDK SHDQAVRTYQ EHKASMHPVT AMLVGKDLKV D
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi gi num :
4505029
ncbi acc num :
NP_000886.1
ncbi gb acc num :
NM_000895.2
uniprot acc num :
P09960
ncbi mol weight :
66,852 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Synthesis Of Leukotrienes (LT) And Eoxins (EX) Pathway (730334); Aspirin Triggered Resolvin E Biosynthesis Pathway (782386); Leukotriene Biosynthesis Pathway (545300); Leukotriene Biosynthesis Pathway (545457)
ncbi summary :
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
uniprot summary :
LTA4H: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. Belongs to the peptidase M1 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Hydrolase; Lipid Metabolism - arachidonic acid; EC 3.3.2.6. Chromosomal Location of Human Ortholog: 12q22. Cellular Component: nucleoplasm; cytoplasm; cytosol. Molecular Function: peptidase activity; leukotriene-A4 hydrolase activity; metallopeptidase activity; zinc ion binding; epoxide hydrolase activity; aminopeptidase activity. Biological Process: leukotriene biosynthetic process; peptide catabolic process; arachidonic acid metabolic process; leukotriene metabolic process; inflammatory response; proteolysis
size1 :
0.5 mg (E-Coli)
price1 :
1405 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1405
size3 :
0.5 mg (Yeast)
price3 :
1630
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1630
size5 :
1 mg (E-Coli)
price5 :
2370
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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