product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Perforin-1
catalog :
MBS954934
quantity :
0.05 mg (E-Coli)
price :
180 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS954934
products type :
Recombinant Protein
products full name :
Recombinant Rat Perforin-1
products short name :
Perforin-1
products name syn :
Cytolysin; Lymphocyte pore-forming protein
other names :
Perforin-1; Perforin-1; perforin-1; perforin 1; Cytolysin; Lymphocyte pore-forming protein
products gene name :
PRF1
products gene name syn :
PFP
other gene names :
Prf1; Prf1; Cyta; RATCYTA; Pfp; P1
uniprot entry name :
PERF_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
25-554; Partial
sequence length :
554
sequence :
ATRSECKQNHKFVPGVWAAGEGVDVTTLRRSSSFPVNTG
KFLRPDRTCTLCKNALMNDGIQRLPVAIAHWRPHGSHCQ
RNVATTKVSSTEGVAREAAANINNDWRAGLDVNPKPEAN
VHVSVAGSHSKIANFAAEKAHQDQYNFNTDTVECRMYSF
RLAQKPPLHPDFRKALKNLPHNFNSSTEHAYRRLISSYG
THFITAVDLGGRVSVLTALRTCQLTLDGLTADEVGDCLS
VEAQVSIGAQASVSSEYKACEEKKKQHKIATSFHQTYRE
RHVEVLGGPLDSSNDLLFGNQATPEHFSTWIASLPTRPD
VVDYSLEPLHILLEDSDPKREALRQAISHYVMSRARWRD
CNRPCRAGQHKSSRDSCQCVCQDSNVTNQDCCPRQRGLA
KLMVRNFQAKGLWGDYITSTDAYLKVFFGGQEIRTGVVW
NNNHPSWSDKMDFGNVLLSTGGPLRVQVWDADNGWDDDL
LGTCDKSPKSGFHEVNCPLNHGSIKFIYQANCLPDLTGE
TCLEYAPQGLLGDPRGNRSGAVW
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
products references :
Molecular cloning of rat cytolysin.Ishikawa H., Shinkai Y., Yagita H., Yue C.C., Henkart P.A., Sawada S., Young H.A., Reynolds C.W., Okumura K.J. Immunol. 143:3069-3073(1989)
ncbi gi num :
548477
ncbi acc num :
P35763.1
uniprot acc num :
P35763
ncbi mol weight :
62.9kD
ncbi pathways :
Allograft Rejection Pathway (83511); Allograft Rejection Pathway (535); Apoptosis Pathway (219785); Autoimmune Thyroid Disease Pathway (83509); Autoimmune Thyroid Disease Pathway (533); Graft-versus-host Disease Pathway (83512); Graft-versus-host Disease Pathway (536); Natural Killer Cell Mediated Cytotoxicity Pathway (83471); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Type I Diabetes Mellitus Pathway (83487)
ncbi summary :
cytolytic factor present in cytoplasmic granules [RGD, Feb 2006]
size1 :
0.05 mg (E-Coli)
price1 :
180 USD
size2 :
0.2 mg (E-Coli)
price2 :
490
size3 :
0.5 mg (E-Coli)
price3 :
715
size4 :
0.05 mg (Baculovirus)
price4 :
950
size5 :
1 mg (E-Coli)
price5 :
1170
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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