catalog number :
MBS954879
products type :
Recombinant Protein
products full name :
Recombinant Mouse 14-3-3 protein gamma (Ywhag)
products short name :
14-3-3 protein gamma (Ywhag)
products name syn :
14-3-3 protein gammaCleaved into the following chain:; 1. 14-3-3 protein gamma, N-terminally processed
other names :
14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 gamma; 14-3-3 protein gamma subtype; 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
products gene name :
Ywhag
other gene names :
Ywhag; Ywhag; D7Bwg1348e; 14-3-3gamma
uniprot entry name :
1433G_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-247
sequence :
MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD DGGEGNN
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
ncbi acc num :
NP_061359.2
ncbi gb acc num :
NM_018871.3
ncbi mol weight :
28,303 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway (1000434); Activation Of BH3-only Proteins Pathway (1000433); Apoptosis Pathway (970512); Calcium Regulation In The Cardiac Cell Pathway (198327); Cell Cycle Pathway (971095); Cell Cycle, Mitotic Pathway (971092); Cell Cycle Pathway (83251); Cell Cycle Pathway (198407); Cell Cycle Pathway (463); Centrosome Maturation Pathway (1000824)
uniprot summary :
14-3-3 gamma: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Homodimer. Interacts with SAMSN1. Interacts with RAF1, SSH1 and CRTC2/TORC2. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with GAB2. Interacts with MDM4 (phosphorylated); negatively regulates MDM4 activity toward TP53. Interacts with PKA-phosphorylated AANAT. Highly expressed in brain, skeletal muscle, and heart. Belongs to the 14-3-3 family. Protein type: Adaptor/scaffold. Cellular Component: focal adhesion; membrane; cytoplasm; intracellular; myelin sheath. Molecular Function: protein domain specific binding; insulin-like growth factor receptor binding; protein binding; protein kinase C binding; receptor tyrosine kinase binding. Biological Process: cellular response to insulin stimulus; regulation of neuron differentiation; regulation of synaptic plasticity; protein targeting
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)