Recombinant Human V-type proton ATPase subunit C 1 (ATP6V1C1) | MyBioSource MBS954865 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human V-type proton ATPase subunit C 1 (ATP6V1C1)

catalog :

MBS954865

quantity :

0.5 mg (E-Coli)

price :

1150 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS954865

products type :

Recombinant Protein

products full name :

Recombinant Human V-type proton ATPase subunit C 1 (ATP6V1C1)

products short name :

V-type proton ATPase subunit C 1 (ATP6V1C1)

products name syn :

V-type proton ATPase subunit C 1; V-ATPase subunit C 1; Vacuolar proton pump subunit C 1

other names :

V-type proton ATPase subunit C 1; V-type proton ATPase subunit C 1; V-type proton ATPase subunit C 1; V-ATPase C subunit; H+ -ATPase C subunit; V-ATPase subunit C 1; vacuolar proton pump C subunit; vacuolar ATP synthase subunit C; vacuolar proton pump subunit C 1; vacuolar proton pump, 42-kD subunit; H+-transporting ATPase chain C, vacuolar; vacuolar proton-ATPase, subunit C, VI domain; subunit C of vacuolar proton-ATPase V1 domain; H(+)-transporting two-sector ATPase, subunit C; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1; Vacuolar proton pump subunit C 1

products gene name :

ATP6V1C1

products gene name syn :

ATP6V1C1; ATP6C; ATP6D; VATC

other gene names :

ATP6V1C1; ATP6V1C1; VATC; Vma5; ATP6C; ATP6D; ATP6C; ATP6D; VATC; V-ATPase subunit C 1

uniprot entry name :

VATC1_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-382

sequence length :

381

sequence :

TEFWLISAP GEKTCQQTWE KLHAATSKNN NLAVTSKFNI PDLKVGTLDV LVGLSDELAK LDAFVEGVVK KVAQYMADVL EDSKDKVQEN LLANGVDLVT YITRFQWDMA KYPIKQSLKN ISEIIAKGVT QIDNDLKSRA SAYNNLKGNL QNLERKNAGS LLTRSLAEIV KKDDFVLDSE YLVTLLVVVP KLNHNDWIKQ YETLAEMVVP RSSNVLSEDQ DSYLCNVTLF RKAVDDFRHK ARENKFIVRD FQYNEEEMKA DKEEMNRLST DKKKQFGPLV RWLKVNFSEA FIAWIHVKAL RVFVESVLRY GLPVNFQAML LQPNKKTLKK LREVLHELYK HLDSSAAAII DAPMDIPGLN LSQQEYYPYV YYKIDCNLLE FK

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

ncbi gi num :

4502315

ncbi acc num :

NP_001686.1

ncbi gb acc num :

NM_001695.4

uniprot acc num :

P21283

ncbi mol weight :

43,942 Da

ncbi pathways :

Collecting Duct Acid Secretion Pathway (147586); Collecting Duct Acid Secretion Pathway (147560); Disease Pathway (530764); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (515); Insulin Receptor Recycling Pathway (106438); Iron Uptake And Transport Pathway (187191); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Oxidative Phosphorylation Pathway (82942); Oxidative Phosphorylation Pathway (303)

ncbi summary :

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. [provided by RefSeq, Jul 2008]

uniprot summary :

ATP6V1C1: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase C subunit family. Protein type: Membrane protein, integral; Transporter; EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Hydrolase. Chromosomal Location of Human Ortholog: 8q22.3. Cellular Component: apical part of cell; lysosomal membrane; plasma membrane; proton-transporting two-sector ATPase complex; cytoplasmic vesicle; cytosol. Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism; protein binding; transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism. Biological Process: interaction with host; proton transport; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; transferrin transport; transmembrane transport

size1 :

0.5 mg (E-Coli)

price1 :

1150 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1150

size3 :

0.5 mg (Yeast)

price3 :

1380

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1380

size5 :

1 mg (E-Coli)

price5 :

1835

more info or order :

MyBioSource product webpage