catalog number :
MBS954218
products type :
Recombinant Protein
products full name :
Recombinant Mouse Glutamate [NMDA] receptor subunit epsilon-1 (Grin2a), partial
products short name :
Glutamate [NMDA] receptor subunit epsilon-1 (Grin2a), partial
products name syn :
Recombinant Glutamate [NMDA] receptor subunit epsilon-1 (Grin2a), partial; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A
other names :
glutamate; Glutamate [NMDA] receptor subunit epsilon-1; glutamate [NMDA] receptor subunit epsilon-1; glutamate [NMDA] receptor subunit epsilon-1; GluRepsilon1; N-methyl D-aspartate receptor subtype 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); N-methyl D-aspartate receptor subtype 2A
products gene name syn :
Grin2a
other gene names :
Grin2a; Grin2a; NR2A; GluN2A; NMDAR2A; NMDAR2A; NR2A
uniprot entry name :
NMDE1_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Mus musculus (Mouse)
ncbi acc num :
NP_032196.2
ncbi gb acc num :
NM_008170.2
ncbi mol weight :
165,421 Da
ncbi pathways :
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (640681); Alcoholism Pathway (585577); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83294); Alzheimer's Disease Pathway (509); Amphetamine Addiction Pathway (547634); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (83296); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); CREB Phosphorylation Through The Activation Of CaMKII Pathway (640688)
uniprot summary :
NMDAR2A: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. Protein type: Channel, ligand-gated; Membrane protein, multi-pass; Membrane protein, integral. Cellular Component: presynaptic membrane; postsynaptic membrane; synaptic vesicle; neuron projection; cell surface; membrane; endoplasmic reticulum; postsynaptic density; integral to membrane; dendritic spine; plasma membrane; terminal button; synapse; cell junction; N-methyl-D-aspartate selective glutamate receptor complex. Molecular Function: voltage-gated cation channel activity; protein dimerization activity; neurotransmitter binding; glutamate receptor binding; zinc ion binding; metal ion binding; calcium channel activity; ion channel activity; receptor activity; protein kinase binding; ATPase binding; protein binding; extracellular-glutamate-gated ion channel activity; glutamate binding; ionotropic glutamate receptor activity; protein heterodimerization activity; N-methyl-D-aspartate selective glutamate receptor activity; protein complex binding; cell adhesion molecule binding; cation channel activity; receptor binding. Biological Process: regulation of long-term neuronal synaptic plasticity; startle response; positive regulation of apoptosis; rhythmic process; regulation of synaptic plasticity; locomotory behavior; sensory perception of pain; dopamine metabolic process; synaptic transmission; protein localization; learning and/or memory; transport; calcium ion transport; response to wounding; visual learning; locomotion; cation transport; serotonin metabolic process; protein tetramerization; response to drug; regulation of synaptic transmission; synaptic transmission, glutamatergic; regulation of action potential; response to amphetamine; learning; sleep; memory; detection of mechanical stimulus involved in sensory perception of pain; regulation of membrane potential; response to ethanol; regulation of postsynaptic membrane potential; neurogenesis; directional locomotion; ionotropic glutamate receptor signaling pathway; ion transport; regulation of sensory perception of pain; regulation of excitatory postsynaptic membrane potential; negative regulation of protein catabolic process