catalog number :
MBS954187
products type :
Recombinant Protein
products full name :
Recombinant Rat Sn1-specific diacylglycerol lipase beta (Daglb)
products short name :
Sn1-specific diacylglycerol lipase beta (Daglb)
products name syn :
Recombinant Sn1-specific diacylglycerol lipase beta (Daglb); Sn1-specific diacylglycerol lipase beta; DGL-beta EC= 3.1.1.-
other names :
Sn1-specific diacylglycerol lipase beta; Sn1-specific diacylglycerol lipase beta; sn1-specific diacylglycerol lipase beta; DGL-beta; diacylglycerol lipase, beta
products gene name syn :
Daglb
other gene names :
Daglb; Daglb; RGD1310193; DGL-beta
uniprot entry name :
DGLB_RAT
sequence positions :
1-668
sequence :
MPGMVLFGRRWSLASDDLVFPGSFELFLRVLWWIASLTL
YLMHRRKLDCPGGVLLSTYLIVLLVLLAVIIGIVLAIVC
VSMRGTICNPGPRKSMSKLLYIRLALFLPEMVWASLGAA
WVAKGIQCDRTVVIGIIATVIVSWIVIAATMVTIVFVFD
PLGGKMAPYPPCIPEHLDSNSSNHLLTGLRTAAKSVWET
RVQCCCCCIGQDDNTRVAFSSTADLFSTYFSDTDLVPSD
IAAGFTLLHQQQDKISHSREPSEVVTHTPGQPQETELDA
EVENCHHYMPFSPVCSPWPVCVLNSSRVELCRTGNNFCR
GRDIEYDAVEGDEHHCHFASILKTTGLQYRDFIHVSFHD
KVYELPFIVVLDHRKESVVVAVRGTMSLQDVLTDLSAES
ENLELDIELQDCVAHKGIAQAARYIYRRLVNDGILSQAF
SVAPEYRLVVVGHSLGAGAAALLAIMLRGAYPQVRAYAF
SPPRGLLSKSLFEYSKDFVVSLILGMDVIPRLSVANMED
LKRRILRVIANCNKPKYKILLHGCWYSVFGGSPDNFPTE
LDEGNQGALTQPLLGEQTLLTRCSPGYCSGDSPLDSPKY
PTLYPPGRIIHLEEEGGSGRFGCCSAAQYRARWAHETEF
SKILIGPKMLIDHMPDVMIRALDRVVADRTACVSCPGQG
GSNVP
form :
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Rattus norvegicus (Rat)
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
ncbi mol weight :
73,771 Da
ncbi pathways :
Arachidonate Production From DAG Pathway 648935!!Effects Of PIP2 Hydrolysis Pathway 648934!!G Alpha (q) Signalling Events Pathway 648933!!GPCR Downstream Signaling Pathway 648929!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 648949!!Hemostasis Pathway 648959!!Platelet Activation, Signaling And Aggregation Pathway 648969!!Retrograde Endocannabinoid Signaling Pathway 537882!!Retrograde Endocannabinoid Signaling Pathway 539806!!Signal Transduction Pathway 648750
uniprot summary :
Function: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses . By similarity. Cofactor: Calcium . By similarity. Subcellular location: Cell membrane; Multi-pass membrane protein . By similarity. Tissue specificity: Expressed in corticostriatal and hippocampal slices. Highly expressed in striatal neurons (at protein level). Ref.2. Sequence similarities: Belongs to the AB hydrolase superfamily. Lipase family.
size :
1 mg (E Coli Derived)