catalog number :
MBS953449
products type :
Recombinant Protein
products full name :
Recombinant Bovine Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)
products short name :
Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)
products name syn :
Recombinant Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2); Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2
other names :
Gamma-aminobutyric acid receptor subunit beta-2; Gamma-aminobutyric acid receptor subunit beta-2; gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2; gamma-aminobutyric acid (GABA) A receptor, beta 2<; GABA(A) receptor subunit beta-2
products gene name syn :
GABRB2
other gene names :
GABRB2; GABRB2
uniprot entry name :
GBRB2_BOVIN
sequence positions :
24-239
sequence :
SVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM
NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPL
NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL
HPDGTVLYGLRITTTTACMMDLRRYPLDEQNCTLEIESY
GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITK
KVVFSTGSYPRLSLSFKLKRN
form :
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Bos taurus (Bovine)
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
ncbi mol weight :
54,451 Da
ncbi pathways :
GABA A Receptor Activation Pathway 637119!!GABA Receptor Activation Pathway 637118!!GABAergic Synapse Pathway 377249!!GABAergic Synapse Pathway 377129!!Ion Channel Transport Pathway 636787!!Ligand-gated Ion Channel Transport Pathway 636789!!Morphine Addiction Pathway 552679!!Morphine Addiction Pathway 554808!!Neuroactive Ligand-receptor Interaction Pathway 84292!!Neuroactive Ligand-receptor Interaction Pathway 462
uniprot summary :
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Ref.2. Subunit structure: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1. Interacts with KCTD8, KCTD12 and KCTD16; this interaction determines the pharmacology and kinetics of the receptor response, the KCTD proteins markedly accelerating the GABA-B response, although to different extents . By similarity. Subcellular location: Cell junction synapse postsynaptic cell membrane; Multi-pass membrane protein . By similarity. Cell membrane; Multi-pass membrane protein . By similarity. Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily. [View classification]
size :
1 mg (E Coli Derived)