Recombinant Human Metallothionein-3 (MT3) | MyBioSource MBS953195 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Metallothionein-3 (MT3)

catalog :

MBS953195

quantity :

0.01 mg (E-Coli)

price :

160 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS953195

products type :

Recombinant Protein

products full name :

Recombinant Human Metallothionein-3 (MT3)

products short name :

[Metallothionein-3 (MT3)]

products name syn :

[Metallothionein-3; MT-3; GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III]

other names :

[metallothionein-3; Metallothionein-3; metallothionein-3; MT-3; MT-III; metallothionein-III; growth inhibitory factor; metallothionein 3 (growth inhibitory factor (neurotrophic)); metallothionein 3; GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III]

products gene name :

[MT3]

other gene names :

[MT3; MT3; GIF; GIFB; GRIF; ZnMT3; MT-3; GIF; MT-III]

uniprot entry name :

MT3_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

[1-68aa; Full Length]

sequence length :

sequence :

MDPETCPCPSGGSCTCADSCKCEGCKCTSCKKSCCSCCP
AECEKCAKDCVCKGGEAAEAEAEKCSCCQ

purity :

>=90%

form :

Liquid containing glycerol

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

image1 heading :

SDS-Page

other info1 :

Species: Homo sapiens (Human)

other info2 :

Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

products categories :

Neuroscience

products description :

Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.

ncbi gi num :

5174762

ncbi acc num :

NP_005945.1

ncbi gb acc num :

NM_005954.2

uniprot acc num :

P25713

ncbi mol weight :

6,927 Da

ncbi summary :

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. This gene family member displays tissue-specific expression, and contains a threonine insert near its N-terminus and a glutamate-rich hexapeptide insert near its C-terminus relative to the proteins encoded by other gene family members. It plays an important role in zinc and copper homeostasis, and is induced under hypoxic conditions. The encoded protein is a growth inhibitory factor, and reduced levels of the protein are observed in the brains of individuals with some metal-linked neurodegenerative disorders such as Alzheimer's disease. [provided by RefSeq, Sep 2017]

uniprot summary :

MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; intracellular; inclusion body. Molecular Function: antioxidant activity; protein binding; copper ion binding; zinc ion binding; caspase inhibitor activity; drug binding; cadmium ion binding; protein kinase activator activity. Biological Process: positive regulation of catalytic activity; negative regulation of autophagy; removal of superoxide radicals; positive regulation of transcription, DNA-dependent; negative regulation of axon extension; negative regulation of caspase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; zinc ion homeostasis; cadmium ion homeostasis; cellular lipid catabolic process; histone modification; protein kinase B signaling cascade; negative regulation of neuron apoptosis; cholesterol catabolic process; regulation of response to food; protein stabilization; activation of protein kinase B; cellular zinc ion homeostasis; zinc ion transport; regulation of protein amino acid glycosylation; leptin-mediated signaling pathway; astrocyte development; cell proliferation; cellular metal ion homeostasis; protein import into nucleus, translocation; negative regulation of oxidoreductase activity; response to hypoxia; energy reserve metabolic process; positive regulation of protein amino acid phosphorylation; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis

size1 :

0.01 mg (E-Coli)

price1 :

160 USD

size2 :

0.05 mg (E-Coli)

price2 :

200

size3 :

0.1 mg (E-Coli)

price3 :

295

size4 :

0.2 mg (E-Coli)

price4 :

480

size5 :

0.5 mg (E-Coli)

price5 :

790

size6 :

1 mg (E-Coli)

price6 :

1215

more info or order :

MyBioSource product webpage