catalog number :
MBS953086
products type :
Recombinant Protein
products full name :
Recombinant Mouse Mannose-binding protein C (Mbl2)
products short name :
Mannose-binding protein C (Mbl2)
products name syn :
Mannose-binding protein C; MBP-C; Mannan-binding protein; RA-reactive factor P28A subunit; RARF/P28A
other names :
mannose-binding protein C; Mannose-binding protein C; mannose-binding protein C; RARF/P28A; mannan-binding protein; mannose binding lectin (C); RA-reactive factor P28A subunit; mannose binding lectin, liver (C); mannose-binding lectin (protein C) 2; Mannan-binding protein; RA-reactive factor P28A subunit; RARF/P28A
products gene name :
Mbl2
other gene names :
Mbl2; Mbl2; MBL; L-MBP; MBL-C; MBP-C; MBP-C; RARF/P28A
uniprot entry name :
MBL2_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
19-244
sequence :
ET LTEGVQNSCP VVTCSSPGLN GFPGKDGRDG AKGEKGEPGQ GLRGLQGPPG KVGPTGPPGN PGLKGAVGPK GDRGDRAEFD TSEIDSEIAA LRSELRALRN WVLFSLSEKV GKKYFVSSVK KMSLDRVKAL CSEFQGSVAT PRNAEENSAI QKVAKDIAYL GITDVRVEGS FEDLTGNRVR YTNWNDGEPN NTGDGEDCVV ILGNGKWNDV PCSDSFLAIC EFSD
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
products description :
Mbl2
ncbi acc num :
NP_034906.1
ncbi gb acc num :
NM_010776.1
ncbi mol weight :
25,957 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (926086); Creation Of C4 And C2 Activators Pathway (926088); Immune System Pathway (926012); Initial Triggering Of Complement Pathway (926087); Innate Immune System Pathway (926045); Lectin Pathway Of Complement Activation (926089); Phagosome Pathway (153914); Phagosome Pathway (153859)
uniprot summary :
MBL2: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Protein type: Secreted; Secreted, signal peptide. Cellular Component: extracellular space; collagen; extracellular region. Molecular Function: mannose binding; protease binding; protein self-association; galactose binding; calcium ion binding; carbohydrate binding; calcium-dependent protein binding; receptor binding. Biological Process: defense response to Gram-positive bacterium; killing by host of symbiont cells; immune system process; positive regulation of phagocytosis; innate immune response; complement activation, lectin pathway; complement activation, classical pathway; negative regulation of viral reproduction
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)