Recombinant Mouse Histone H1.1(Hist1h1a) | MyBioSource MBS952901 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Mouse Histone H1.1(Hist1h1a)

catalog :

MBS952901

quantity :

0.05 mg (E-Coli)

price :

190 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS952901

products type :

Recombinant Protein

products full name :

Recombinant Mouse Histone H1.1(Hist1h1a)

products short name :

Histone H1.1

products name syn :

H1 VAR.3; Histone H1a; H1a

other names :

histone H1.1; Histone H1.1; histone H1.1; histone cluster 1, H1a; H1 VAR.3; Histone H1a; H1a

products gene name :

Hist1h1a

products gene name syn :

H1f1

other gene names :

Hist1h1a; Hist1h1a; H1a; H1.1; H1f1; H1var3; H1a; H1f1; H1a

uniprot entry name :

H11_MOUSE

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

2-213

sequence length :

213

sequence :

SETAPVAQAASTATEKPAAAKKTKKPAKAAAPRKKPAGP
SVSELIVQAVSSSKERSGVSLAALKKSLAAAGYDVEKNN
SRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKAESKAI
TTKVSVKAKASGAAKKPKKTAGAAAKKTVKTPKKPKKPA
VSKKTSKSPKKPKVVKAKKVAKSPAKAKAVKPKASKAKV
TKPKTPAKPKKAAPKKK

purity :

Greater than 90% as determined by SDS-PAGE.

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

products description :

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

products references :

Isolation and characterization of two replication-dependent mouse H1 histone genes.Dong Y., Sirotkin A.M., Yang Y.-S., Brown D.T., Sittman D.B., Skoultchi A.I.Nucleic Acids Res. 22:1421-1428(1994) Expression of murine H1 histone genes during postnatal development.Franke K., Drabent B., Doenecke D.Biochim. Biophys. Acta 1398:232-242(1998) The human and mouse replication-dependent histone genes.Marzluff W.F., Gongidi P., Woods K.R., Jin J., Maltais L.J.Genomics 80:487-498(2002) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. In vivo phosphorylation of histone H1 variants during the cell cycle.Talasz H., Helliger W., Puschendorf B., Lindner H.Biochemistry 35:1761-1767(1996) Spermatogenesis in mice is not affected by histone H1.1 deficiency.Rabini S., Franke K., Saftig P., Bode C., Doenecke D., Drabent B.Exp. Cell Res. 255:114-124(2000) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.Mol. Cell 50:919-930(2013) Citrullination regulates pluripotency and histone H1 binding to chromatin.Christophorou M.A., Castelo-Branco G., Halley-Stott R.P., Oliveira C.S., Loos R., Radzisheuskaya A., Mowen K.A., Bertone P., Silva J.C., Zernicka-Goetz M., Nielsen M.L., Gurdon J.B., Kouzarides T.Nature 507:104-108(2014)

ncbi gi num :

21426823

ncbi acc num :

NP_085112.1

ncbi gb acc num :

NM_030609.3

uniprot acc num :

P43275

ncbi mol weight :

49kD

ncbi summary :

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]

uniprot summary :

H1F1: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. Belongs to the histone H1/H5 family. Protein type: DNA-binding. Cellular Component: chromosome; nucleosome; nucleus. Molecular Function: DNA binding; protein binding. Biological Process: nucleosome assembly; spermatogenesis

size1 :

0.05 mg (E-Coli)

price1 :

190 USD

size2 :

0.2 mg (E-Coli)

price2 :

460

size3 :

0.5 mg (E-Coli)

price3 :

750

size4 :

0.05 mg (Baculovirus)

price4 :

965

size5 :

1 mg (E-Coli)

price5 :

1180

more info or order :

MyBioSource product webpage