product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Chondroitin sulfate proteoglycan 4 (Cspg4), partial
catalog :
MBS952539
quantity :
0.5 mg (E-Coli)
price :
1435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS952539
products type :
Recombinant Protein
products full name :
Recombinant Rat Chondroitin sulfate proteoglycan 4 (Cspg4), partial
products short name :
Chondroitin sulfate proteoglycan 4 (Cspg4), partial
products name syn :
Chondroitin sulfate proteoglycan 4; Chondroitin sulfate proteoglycan NG2; HSN tumor-specific antigen
other names :
chondroitin sulfate proteoglycan 4; Chondroitin sulfate proteoglycan 4; chondroitin sulfate proteoglycan 4; HSN tumor-specific antigen; membrane-spanning proteoglycan NG2; chondroitin sulfate proteoglycan NG2; chondroitin sulfate proteoglycan 4; Chondroitin sulfate proteoglycan NG2; HSN tumor-specific antigen
products gene name :
Cspg4
products gene name syn :
Cspg4; Ng2
other gene names :
Cspg4; Cspg4; Ng2; Ng2
uniprot entry name :
CSPG4_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rattus norvegicus (Rat)
ncbi gi num :
13591932
ncbi acc num :
NP_112284.1
ncbi gb acc num :
NM_031022.1
uniprot acc num :
Q00657
ncbi mol weight :
251,909 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (935467); CS/DS Degradation Pathway (935473); Chondroitin Sulfate Biosynthesis Pathway (935471); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (935470); Dermatan Sulfate Biosynthesis Pathway (935472); Disease Pathway (936186); Glycosaminoglycan Metabolism Pathway (935458); Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway (935466); MPS I - Hurler Syndrome Pathway (936207); MPS II - Hunter Syndrome Pathway (936208)
ncbi summary :
extracellular matrix protein secreted by many cell types; member of the large chondroitin sulfate proteoglycan (CSPG) family; may be involved with angiogenesis -dependent processes such as wound healing or tumor growth [RGD, Feb 2006]
uniprot summary :
NG2: a transmembrane chondrotin sulfate proteoglycan expressed on several types of immature progenitor cells and human malignant melanoma cells. Plays a role in cell proliferation and motility of endothelial cells during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. May regulate MPP16-dependent degradation and invasion of type I collagen participating to melanoma cells invasion properties. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through Cdc42, ACK1 and P130Cas. May activate FAK and ERK signaling cascades. PKC-alpha-mediated NG2 phosphorylation may be a key step for initiating cell polarization and motility. Protein type: Cell adhesion; Membrane protein, integral. Cellular Component: cell surface; cell projection; focal adhesion; integral to plasma membrane; apical plasma membrane; plasma membrane. Molecular Function: collagen binding; signal transducer activity; protein kinase binding. Biological Process: cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; activation of MAPK activity; response to lithium ion; tissue remodeling; angiogenesis; signal transduction; glial cell migration; inflammatory response; transmembrane receptor protein tyrosine kinase signaling pathway; neuron remodeling
size1 :
0.5 mg (E-Coli)
price1 :
1435 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1435
size3 :
0.5 mg (Yeast)
price3 :
1660
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1660
size5 :
1 mg (E-Coli)
price5 :
2390
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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