product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Double-strand break repair protein MRE11A (MRE11A)
catalog :
MBS952111
quantity :
1 mg (E Coli Derived
price :
2595 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS952111
products type :
Recombinant Protein
products full name :
Recombinant Human Double-strand break repair protein MRE11A (MRE11A)
products short name :
Double-strand break repair protein MRE11A(MRE11A)
other names :
double-strand break repair protein MRE11A isoform 2; Double-strand break repair protein MRE11A; double-strand break repair protein MRE11A; AT-like disease; MRE11 homolog 1; MRE11 homolog A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; DNA recombination and repair protein; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A
products gene name :
MRE11A
other gene names :
MRE11A; MRE11A; ATLD; HNGS1; MRE11; MRE11B; HNGS1; MRE11; MRE11 homolog 1; MRE11 homolog A
uniprot entry name :
MRE11_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-708
sequence length :
680
sequence :
STADALDDE NTFKILVATD IHLGFMEKDA VRGNDTFVTL DEILRLAQEN EVDFILLGGD LFHENKPSRK TLHTCLELLR KYCMGDRPVQ FEILSDQSVN FGFSKFPWVN YQDGNLNISI PVFSIHGNHD DPTGADALCA LDILSCAGFV NHFGRSMSVE KIDISPVLLQ KGSTKIALYG LGSIPDERLY RMFVNKKVTM LRPKEDENSW FNLFVIHQNR SKHGSTNFIP EQFLDDFIDL VIWGHEHECK IAPTKNEQQL FYISQPGSSV VTSLSPGEAV KKHVGLLRIK GRKMNMHKIP LHTVRQFFME DIVLANHPDI FNPDNPKVTQ AIQSFCLEKI EEMLENAERE RLGNSHQPEK PLVRLRVDYS GGFEPFSVLR FSQKFVDRVA NPKDIIHFFR HREQKEKTGE EINFGKLITK PSEGTTLRVE DLVKQYFQTA EKNVQLSLLT ERGMGEAVQE FVDKEEKDAI EELVKYQLEK TQRFLKERHI DALEDKIDEE VRRFRETRQK NTNEEDDEVR EAMTRARALR SQSEESASAF SADDLMSIDL AEQMANDSDD SISAATNKGR GRGRGRRGGR GQNSASRGGS QRGRADTGLE TSTRSRNSKT AVSASRNMSI IDAFKSTRQQ PSRNVTTKNY SEVIEVDESD VEEDIFPTTS KTDQRWSSTS SSKIMSQSQV SKGVDFESSE DDDDDPFMNT SSLRRNRR
purity :
>90%
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi gi num :
24234690
ncbi acc num :
NP_005581.2
ncbi gb acc num :
NM_005590.3
uniprot acc num :
P49959
ncbi mol weight :
77,642 Da
ncbi pathways :
Assembly Of The RAD50-MRE11-NBS1 Complex At DNA Double-strand Breaks Pathway 105868!!BARD1 Signaling Events Pathway 137959!!BRCA1-associated Genome Surveillance Complex (BASC) Pathway 413428!!DNA Repair Pathway 105837!!DNA Damage Response Pathway 198788!!Double-Strand Break Repair Pathway 105861!!Homologous Recombination Repair Pathway 105862!!Homologous Recombination Pathway 198890!!Homologous Recombination Pathway 83046!!Homologous Recombination Pathway 454
ncbi summary :
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)
price :
2595 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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