product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Coilin (COIL)
catalog :
MBS951259
quantity :
0.5 mg (E-Coli)
price :
1375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS951259
products type :
Recombinant Protein
products full name :
Recombinant Human Coilin (COIL)
products short name :
Coilin (COIL)
products name syn :
Coilin; p80
other names :
coilin; Coilin; coilin; p80; coilin p80; coilin; p80-coilin
products gene name :
COIL
products gene name syn :
COIL; CLN80
other gene names :
COIL; COIL; CLN80; p80-coilin; CLN80
uniprot entry name :
COIL_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-576
sequence length :
576
sequence :
MAASETVRLR LQFDYPPPAT PHCTAFWLLV DLNRCRVVTD LISLIRQRFG FSSGAFLGLY LEGGLLPPAE SARLVRDNDC LRVKLEERGV AENSVVISNG DINLSLRKAK KRAFQLEEGE ETEPDCKYSK KHWKSRENNN NNEKVLDLEP KAVTDQTVSK KNKRKNKATC GTVGDDNEEA KRKSPKKKEK CEYKKKAKNP KSPKVQAVKD WANQRCSSPK GSARNSLVKA KRKGSVSVCS KESPSSSSES ESCDESISDG PSKVTLEARN SSEKLPTELS KEEPSTKNTT ADKLAIKLGF SLTPSKGKTS GTTSSSSDSS AESDDQCLMS SSTPECAAGF LKTVGLFAGR GRPGPGLSSQ TAGAAGWRRS GSNGGGQAPG ASPSVSLPAS LGRGWGREEN LFSWKGAKGR GMRGRGRGRG HPVSCVVNRS TDNQRQQQLN DVVKNSSTII QNPVETPKKD YSLLPLLAAA PQVGEKIAFK LLELTSSYSP DVSDYKEGRI LSHNPETQQV DIEILSSLPA LREPGKFDLV YHNENGAEVV EYAVTQESKI TVFWKELIDP RLIIESPSNT SSTEPA
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
ncbi gi num :
4758024
ncbi acc num :
NP_004636.1
ncbi gb acc num :
NM_004645.2
uniprot acc num :
P38432
ncbi mol weight :
62,608 Da
ncbi summary :
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
uniprot summary :
coilin: an ubiquitous protein found in nuclear coiled bodies (CBS), nuclear suborganelles involved in the post-transcriptional modification of snRNPs and small nucleolar RNAs. snRNPs undergo 2 -O-methylation and pseudouridylation in CBS. Differential methylation and phosphorylation of coilin likely influences localization among nuclear bodies and the composition and assembly of CBS. Located in the interchromatin space between the nucleolus and the nucleus. Protein type: Oxidoreductase. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: nucleoplasm; Cajal body; membrane; cytoplasm; nucleolus; nucleus. Molecular Function: protein C-terminus binding; identical protein binding; protein binding
size1 :
0.5 mg (E-Coli)
price1 :
1375 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1375
size3 :
0.5 mg (Yeast)
price3 :
1595
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1595
size5 :
1 mg (E-Coli)
price5 :
2290
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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