catalog number :
MBS951056
products type :
Recombinant Protein
products full name :
Recombinant Human Testosterone 17-beta-dehydrogenase 3 (HSD17B3)
products short name :
Testosterone 17-beta-dehydrogenase 3 (HSD17B3)
other names :
testosterone 17-beta-dehydrogenase 3; Testosterone 17-beta-dehydrogenase 3; testosterone 17-beta-dehydrogenase 3; 17-beta-HSD3; 17-beta-HSD 3; 17-beta-hydroxysteroid dehydrogenase type 3; testicular 17-beta-hydroxysteroid dehydrogenase; short chain dehydrogenase/reductase family 12C, member 2; hydroxysteroid (17-beta) dehydrogenase 3; 17-beta-hydroxysteroid dehydrogenase type 3; 17-beta-HSD 3; Testicular 17-beta-hydroxysteroid dehydrogenase
products gene name :
HSD17B3
other gene names :
HSD17B3; HSD17B3; EDH17B3; SDR12C2; EDH17B3; 17-beta-HSD 3
uniprot entry name :
DHB3_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-310
sequence :
MGDVLEQFFI LTGLLVCLAC LAKCVRFSRC VLLNYWKVLP KSFLRSMGQW AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV KIIQADFTKD DIYEHIKEKL AGLEIGILVN NVGMLPNLLP SHFLNAPDEI QSLIHCNITS VVKMTQLILK HMESRQKGLI LNISSGIALF PWPLYSMYSA SKAFVCAFSK ALQEEYKAKE VIIQVLTPYA VSTAMTKYLN TNVITKTADE FVKESLNYVT IGGETCGCLA HEILAGFLSL IPAWAFYSGA FQRLLLTHYV AYLKLNTKVR
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_000188.1
ncbi gb acc num :
NM_000197.1
ncbi mol weight :
34,516 Da
ncbi pathways :
Androgen Biosynthesis Pathway 106154!!Fatty Acyl-CoA Biosynthesis Pathway 106115!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Metabolism Of Steroid Hormones And Vitamin D Pathway 106150!!Prostate Cancer Pathway 755440!!Steroid Biosynthesis Pathway 198866!!Steroid Hormone Biosynthesis Pathway 82940!!Steroid Hormone Biosynthesis Pathway 301
ncbi summary :
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)