Recombinant Human Inhibin alpha chain (INHA) | MyBioSource MBS951054 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Inhibin alpha chain (INHA)

catalog :

MBS951054

quantity :

0.5 mg (E-Coli)

price :

870 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS951054

products type :

Recombinant Protein

products full name :

Recombinant Human Inhibin alpha chain (INHA)

products short name :

Inhibin alpha chain (INHA)

products name syn :

Inhibin alpha chain

other names :

inhibin alpha chain preproprotein; Inhibin alpha chain; inhibin alpha chain; A-inhibin subunit; inhibin, alpha

products gene name :

INHA

other gene names :

INHA; INHA

uniprot entry name :

INHA_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

233-366

sequence length :

134

sequence :

STPLMSWP WSPSALRLLQ RPPEEPAAHA NCHRVALNIS FQELGWERWI VYPPSFIFHY CHGGCGLHIP PNLSLPVPGA PPTPAQPYSL LPGAQPCCAA LPGTMRPLHV RTTSDGGYSF KYETVPNLLT QHCACI

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

products description :

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

ncbi gi num :

4504697

ncbi acc num :

NP_002182.1

ncbi gb acc num :

NM_002191.3

uniprot acc num :

P05111

ncbi mol weight :

18kD

ncbi pathways :

Glycoprotein Hormones Pathway (160989); Metabolism Of Proteins Pathway (106230); Ovarian Infertility Genes Pathway (198801); Peptide Hormone Biosynthesis Pathway (160988); Peptide Hormone Metabolism Pathway (771603)

ncbi summary :

This gene encodes the alpha subunit of inhibins A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion.[provided by RefSeq, Dec 2010]

uniprot summary :

INHA: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2q35. Cellular Component: photoreceptor inner segment; photoreceptor outer segment; cell soma; extracellular region. Molecular Function: protein binding; growth factor activity; protein heterodimerization activity; hormone activity; cytokine activity; transforming growth factor beta receptor binding; receptor binding. Biological Process: negative regulation of B cell differentiation; hemoglobin biosynthetic process; nervous system development; regulation of cell cycle; male gonad development; signal transduction; regulation of cell proliferation; negative regulation of follicle-stimulating hormone secretion; negative regulation of interferon-gamma biosynthetic process; negative regulation of cell cycle; regulation of apoptosis; response to external stimulus; cell surface receptor linked signal transduction; ovarian follicle development; negative regulation of macrophage differentiation; cell-cell signaling; regulation of MAPKKK cascade; negative regulation of phosphorylation; erythrocyte differentiation; positive regulation of follicle-stimulating hormone secretion; cell cycle arrest; cell differentiation; skeletal development; cell development

size1 :

0.5 mg (E-Coli)

price1 :

870 USD

size2 :

0.05 mg (Baculovirus)

price2 :

870

size3 :

0.5 mg (Yeast)

price3 :

1095

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1095

size5 :

1 mg (E-Coli)

price5 :

1270

more info or order :

MyBioSource product webpage