Recombinant Human 3-ketoacyl-CoA thiolase, mitochondrial | MyBioSource MBS950688 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human 3-ketoacyl-CoA thiolase, mitochondrial

catalog :

MBS950688

quantity :

0.05 mg (E-Coli)

price :

190 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS950688

products type :

Recombinant Protein

products full name :

Recombinant Human 3-ketoacyl-CoA thiolase, mitochondrial

products short name :

3-ketoacyl-CoA thiolase

products name syn :

Acetyl-CoA acyltrans ferase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1

other names :

3-ketoacyl-CoA thiolase, mitochondrial; 3-ketoacyl-CoA thiolase, mitochondrial; 3-ketoacyl-CoA thiolase, mitochondrial; acetyl-CoA acyltransferase 2; Acetyl-CoA acyltransferase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1

products gene name :

ACAA2

other gene names :

ACAA2; ACAA2; DSAEC

uniprot entry name :

THIM_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

17-397

sequence length :

397

sequence :

FGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVI
MGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGS
GFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVR
FGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKH
KISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTK
KGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNA
SGVADGAGAVIIASEDAVKKH

purity :

Greater than 90% as determined by SDS-PAGE.

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

products categories :

Metabolism

products description :

Abolishes BNIP3-mediated apoptosis and mitochondrial damage.

products references :

Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase.Abe H., Ohtake A., Yamamoto S., Satoh Y., Takayanagi M., Amaya Y., Takiguchi M., Sakuraba H., Suzuki Y., Mori M., Niimi H.Biochim. Biophys. Acta 1216:304-306(1993) Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.Aboulaich N., Vainonen J.P., Stralfors P., Vener A.V.Biochem. J. 383:237-248(2004) Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines.Cao W., Liu N., Tang S., Bao L., Shen L., Yuan H., Zhao X., Lu H.Biochim. Biophys. Acta 1780:873-880(2008) A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)

ncbi gi num :

167614485

ncbi acc num :

NP_006102.2

ncbi gb acc num :

NM_006111.2

uniprot acc num :

P42765

ncbi mol weight :

44.3kD

ncbi pathways :

Fatty Acid Biosynthesis Pathway (198873); Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway (413380); Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway (468246); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Elongation Pathway (82934); Fatty Acid Elongation Pathway (295); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045); Metabolic Pathways (132956)

ncbi summary :

The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]

uniprot summary :

ACAA2: Abolishes BNIP3-mediated apoptosis and mitochondrial damage. Belongs to the thiolase family. Protein type: Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.16; Transferase. Chromosomal Location of Human Ortholog: 18q21.1. Cellular Component: mitochondrial inner membrane; mitochondrion. Molecular Function: acetyl-CoA C-acyltransferase activity; protein binding. Biological Process: cholesterol biosynthetic process; fatty acid metabolic process

size1 :

0.05 mg (E-Coli)

price1 :

190 USD

size2 :

0.05 mg (Yeast)

price2 :

190

size3 :

0.2 mg (E-Coli)

price3 :

460

size4 :

0.2 mg (Yeast)

price4 :

460

size5 :

0.5 mg (E-Coli)

price5 :

750

more info or order :

MyBioSource product webpage