catalog number :
MBS950626
products type :
Recombinant Protein
products full name :
Recombinant Human 3-mercaptopyruvate sulfurtransferase (MPST)
products short name :
3-mercaptopyruvate sulfurtransferase (MPST)
products name syn :
3-mercaptopyruvate sulfurtransferase; MST; EC=2.8.1.2
other names :
3-mercaptopyruvate sulfurtransferase isoform 2; 3-mercaptopyruvate sulfurtransferase; 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; mercaptopyruvate sulfurtransferase
products gene name :
MPST
products gene name syn :
MPST; TST2
other gene names :
MPST; MPST; MST; TST2; TST2; MST
uniprot entry name :
THTM_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-297
sequence :
ASPQLCRAL VSAQWVAEAL RAPRAGQPLQ LLDASWYLPK LGRDARREFE ERHIPGAAFF DIDQCSDRTS PYDHMLPGAE HFAEYAGRLG VGAATHVVIY DASDQGLYSA PRVWWMFRAF GHHAVSLLDG GLRHWLRQNL PLSSGKSQPA PAEFRAQLDP AFIKTYEDIK ENLESRRFQV VDSRATGRFR GTEPEPRDGI EPGHIPGTVN IPFTDFLSQE GLEKSPEEIR HLFQEKKVDL SKPLVATCGS GVTACHVALG AYLCGKPDVP IYDGSWVEWY MRARPEDVIS EGRGKTH
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_001013454.1
ncbi gb acc num :
NM_001013436.2
ncbi mol weight :
35,250 Da
ncbi pathways :
Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Sulfur Metabolism Pathway (83026); Sulfur Metabolism Pathway (417); Sulfur Relay System Pathway (172845); Sulfur Relay System Pathway (171866); Trans-sulfuration Pathway (739008)
ncbi summary :
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
MPST: Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. May have a role in cyanide degradation or in thiosulfate biosynthesis. Protein type: EC 2.8.1.2; Mitochondrial; Transferase; Amino Acid Metabolism - cysteine and methionine. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: neuron projection; mitochondrial inner membrane; synapse; cell junction. Molecular Function: 3-mercaptopyruvate sulfurtransferase activity; thiosulfate sulfurtransferase activity. Biological Process: cyanate catabolic process; response to toxin
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)