catalog number :
MBS950511
products type :
Recombinant Protein
products full name :
Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A)
products short name :
B-cell antigen receptor complex-associated protein alpha chain (CD79A)
products name syn :
B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen=; CD79a
other names :
B-cell antigen receptor complex-associated protein alpha chain isoform 1; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; CD79a antigen (immunoglobulin-associated alpha); membrane-bound immunoglobulin-associated protein; CD79a molecule, immunoglobulin-associated alpha; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a
products gene name :
CD79A
products gene name syn :
CD79A; IGA; MB1
other gene names :
CD79A; CD79A; IGA; MB-1; IGA; MB1
uniprot entry name :
CD79A_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
33-143
sequence :
LWMHKVPA SLMVSLGEDA HFQCPHNSSN NANVTWWRVL HGNYTWPPEF LGPGEDPNGT LIIQNVNKSH GGIYVCRVQE GNESYQQSCG TYLRVRQPPP RPFLDMGEGT KNR
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_001774.1
ncbi gb acc num :
NM_001783.3
ncbi mol weight :
20,786 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway (576249); B Cell Receptor Signaling Pathway (198909); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); BCR Signaling Pathway (138058); Immune System Pathway (106386); Primary Immunodeficiency Pathway (83125); Primary Immunodeficiency Pathway (537); Signaling By The B Cell Receptor (BCR) Pathway (576248)
ncbi summary :
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described. Protein type: Immunoglobulin superfamily; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; external side of plasma membrane; lipid raft. Molecular Function: transmembrane receptor activity. Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation. Disease: Agammaglobulinemia 3, Autosomal Recessive