catalog number :
MBS950471
products type :
Recombinant Protein
products full name :
Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 1 (Adamts1)
products short name :
A disintegrin and metalloproteinase with thrombospondin motifs 1 (Adamts1)
products name syn :
A disintegrin and metalloproteinase with thrombospondin motifs 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; EC=3.4.24.-
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; ADAM-TS 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
products gene name :
Adamts1
other gene names :
Adamts1; Adamts1; C3-C5; METH1; ADAMTS; METH-1; ADAM-TS1; ADAMTS-1; ADAM-TS 1; ADAM-TS1; ADAMTS-1
uniprot entry name :
ATS1_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
254-968
sequence :
FVSSPRY VETMLVADQS MADFHGSGLK HYLLTLFSVA ARFYKHPSIR NSISLVVVKI LVIYEEQKGP EVTSNAALTL RNFCSWQKQH NSPSDRDPEH YDTAILFTRQ DLCGSHTCDT LGMADVGTVC DPSRSCSVIE DDGLQAAFTT AHELGHVFNM PHDDAKHCAS LNGVSGDSHL MASMLSSLDH SQPWSPCSAY MVTSFLDNGH GECLMDKPQN PIKLPSDLPG TLYDANRQCQ FTFGEESKHC PDAASTCTTL WCTGTSGGLL VCQTKHFPWA DGTSCGEGKW CVSGKCVNKT DMKHFATPVH GSWGPWGPWG DCSRTCGGGV QYTMRECDNP VPKNGGKYCE GKRVRYRSCN IEDCPDNNGK TFREEQCEAH NEFSKASFGN EPTVEWTPKY AGVSPKDRCK LTCEAKGIGY FFVLQPKVVD GTPCSPDSTS VCVQGQCVKA GCDRIIDSKK KFDKCGVCGG NGSTCKKMSG IVTSTRPGYH DIVTIPAGAT NIEVKHRNQR GSRNNGSFLA IRAADGTYIL NGNFTLSTLE QDLTYKGTVL RYSGSSAALE RIRSFSPLKE PLTIQVLMVG HALRPKIKFT YFMKKKTESF NAIPTFSEWV IEEWGECSKT CGSGWQRRVV QCRDINGHPA SECAKEVKPA STRPCADLPC PHWQVGDWSP CSKTCGKGYK KRTLKCVSHD GGVLSNESCD PLKKPKHYID FCTLTQCS
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
ncbi acc num :
NP_033751.3
ncbi gb acc num :
NM_009621.4
ncbi mol weight :
105,801 Da
ncbi pathways :
Endochondral Ossification Pathway (198336)
uniprot summary :
ADAMTS1: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. Protein type: Protease; Secreted; EC 3.4.24.-; Secreted, signal peptide; Motility/polarity/chemotaxis. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; cytoplasm; extracellular region; basement membrane; cytoplasmic vesicle. Molecular Function: heparin binding; peptidase activity; protein binding; zinc ion binding; metallopeptidase activity; hydrolase activity; metal ion binding; metalloendopeptidase activity. Biological Process: negative regulation of angiogenesis; ovulation from ovarian follicle; proteolysis; kidney development
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)