catalog number :
MBS9501836
products type :
ELISA Kit
products full name :
CTGF (Human) OmniKine ELISA Kit
products short name :
[CTGF]
products name syn :
[Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CCN2; HCS24; IGFBP8]
other names :
[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8]
products gene name :
[CTGF]
products gene name syn :
[CTGF]
other gene names :
[CTGF; CTGF; CCN2; NOV2; HCS24; IGFBP8; CCN2; HCS24; IGFBP8; IBP-8; IGF-binding protein 8; IGFBP-8]
specificity :
The OmniKine Human CTGF ELISA is capable of recognizing both recombinant and naturally produced Human CTGF proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference. Human: BMP-4, CTGFL/WISP-2, CYR61, IGF-I, IGF-II, IGF-BP1, NOV, TGF-beta, WISP-1, WISP-3
form :
12 x 8-Well Microstrips
storage stability :
Store at 4 degree C for 6 months.
image1 heading :
Testing Data
other info1 :
Samples: Plasma, serum, lysate. Assay Type: Sandwich ELISA. Detection Range: 63-4000 pg/ml. Sensitivity: 63-4000 pg/ml
other info2 :
Detection Method: Colorimetric 450 nm. Subtype: None
ncbi acc num :
NP_001892.1
ncbi gb acc num :
NM_001901.2
ncbi mol weight :
35,205 Da
ncbi pathways :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); TGF-beta Receptor Signaling Pathway (138024)
ncbi summary :
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]
uniprot summary :
CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q23.2. Cellular Component: cell cortex; cis-Golgi network; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; proteinaceous extracellular matrix. Molecular Function: fibronectin binding; growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding; protein C-terminus binding. Biological Process: aging; angiogenesis; cartilage condensation; cell adhesion; cell differentiation; cell migration; cell-cell signaling; cell-matrix adhesion; epidermis development; fibroblast growth factor receptor signaling pathway; integrin-mediated signaling pathway; lung development; ossification; positive regulation of cell activation; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of JNK cascade; positive regulation of stress fiber formation; regulation of cell growth; regulation of chondrocyte differentiation; regulation of lipid metabolic process; response to amino acid; response to anoxia; response to estradiol; response to glucose stimulus; response to mineralocorticoid stimulus; response to peptide hormone; response to wounding; tissue homeostasis; transcription initiation from RNA polymerase II promoter