catalog number :
MBS9501829
products type :
ELISA Kit
products full name :
BD-2 (Human) OmniKine ELISA Kit
products short name :
[BD-2]
products name syn :
[BD-2; hBD-2; Defensin beta 2; Skin-antimicrobial peptide 1; SAP1; DEFB4; DEFB102; DEFB2; DEFB4P; Beta-defensin 2]
other names :
[beta-defensin 4B; Beta-defensin 4A; beta-defensin 4B; defensin beta 4B; Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1]
products gene name :
[BD-2]
products gene name syn :
[DEFB4A/B]
other gene names :
[DEFB4B; DEFB4A; DEFB4P; DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1]
specificity :
The OmniKine Human BD-2 ELISA is capable of recognizing both recombinant and naturally produced Human BD-2 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference. Human: BD-1 (36 aa), BD-1 (47 aa), BD-3, BD-4
form :
12 x 8-Well Microstrips
storage stability :
Store at 4 degree C for 6 months.
image1 heading :
Testing Data
products description :
Background/Introduction: HTR1F encodes the G-protein coupled receptor for 5-hydroxytryptamine (serotonin). This protein functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
ncbi acc num :
NP_001192195.1
ncbi gb acc num :
NM_001205266.1
ncbi mol weight :
7,038 Da
ncbi pathways :
Beta Defensins Pathway (530759); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
uniprot summary :
defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8p23.1. Cellular Component: extracellular region; extracellular space; Golgi lumen; intracellular. Molecular Function: CCR6 chemokine receptor binding; protein binding. Biological Process: antimicrobial humoral response; chemotaxis; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; G-protein coupled receptor signaling pathway; immune response; killing of cells of other organism