catalog number :
MBS949766
products type :
Recombinant Protein
products full name :
Recombinant Mouse T-cell surface glycoprotein CD3 zeta chain (Cd247)
products short name :
T-cell surface glycoprotein CD3 zeta chain (Cd247)
products name syn :
Recombinant T-cell surface glycoprotein CD3 zeta chain (Cd247); T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain CD_antigen= CD247
other names :
CD247 antigen isoform zeta; T-cell surface glycoprotein CD3 zeta chain; CD247 antigen; CD3-zeta/eta; T-cell receptor T3 eta chain; CD3 antigen, zeta polypeptide; T-cell surface glycoprotein CD3 zeta chain; CD247 antigen; T-cell receptor T3 zeta chain
products gene name syn :
Cd247; Cd3z, Tcrz
other gene names :
Cd247; Cd247; Cd3; T3z; Cd3h; Cd3z; Tcrk; Tcrz; Cd3-eta; Cd3zeta; AW552088; Cd3-zeta; 4930549J05Rik; A430104F18Rik; Cd3z; Tcrz
uniprot entry name :
CD3Z_MOUSE
sequence positions :
22-30
form :
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Tag Information: GST tagged (Host tag may vary. Please inquire for specific tag information). Species: Mus musculus (Mouse)
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
ncbi acc num :
NP_001106862.1
ncbi gb acc num :
NM_001113391.2
ncbi mol weight :
18,637 Da
ncbi pathways :
Adaptive Immune System Pathway 640102!!Chagas Disease (American Trypanosomiasis) Pathway 147810!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Immune System Pathway 640101!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 640127!!Natural Killer Cell Mediated Cytotoxicity Pathway 83276!!Natural Killer Cell Mediated Cytotoxicity Pathway 490!!T Cell Receptor Signaling Pathway 198362!!T Cell Receptor Signaling Pathway 83277!!T Cell Receptor Signaling Pathway 491
uniprot summary :
Function: Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. Subunit structure: Interacts with DOCK2 and TRAT1. Interacts with SHB. Interacts with ZAP70. Interacts (tyrosine phosphorylated) with SHC1 (via SH2 domain). Interacts with PTPRC . By similarity. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Ref.8 Ref.9. Subcellular location: Membrane; Single-pass type I membrane protein. Domain: The ITAM domains mediate interaction with SHB . By similarity. Post-translational modification: Phosphorylated on Tyr residues after T-cell receptor triggering. Sequence similarities: Belongs to the CD3Z/FCER1G family.Contains 3 ITAM domains.
size :
1 mg (E Coli Derived)