catalog number :
MBS949568
products type :
Recombinant Protein
products full name :
Recombinant Mouse NEDD8 (Nedd8)
products short name :
NEDD8 (Nedd8)
products name syn :
NEDD8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8
other names :
NEDD8; NEDD8; NEDD8; NEDD-8; neddylin; ubiquitin-like protein Nedd8; neural precursor cell expressed developmentally down-regulated protein 8; neural precursor cell expressed, developmentally down-regulated gene 8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8
products gene name :
Nedd8
products gene name syn :
Nedd8; Nedd-8
other gene names :
Nedd8; Nedd8; Rub1; Nedd-8; NEDD-8
uniprot entry name :
NEDD8_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
Jan-76
sequence :
MLIKVKTLTG KEIEIDIEPT DKVERIKERV EEKEGIPPQQ QRLIYSGKQM NDEKTAADYK ILGGSVLHLV LALRGG
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
ncbi acc num :
NP_032709.1
ncbi gb acc num :
NM_008683.3
ncbi mol weight :
8,972 Da
ncbi pathways :
Disease Pathway (970606); Loss Of Function Of SMAD2/3 In Cancer Pathway (1000710); Loss Of Function Of SMAD4 In Cancer Pathway (1000704); Loss Of Function Of TGFBR1 In Cancer Pathway (1000716); Loss Of Function Of TGFBR2 In Cancer Pathway (1000713); SMAD2/3 MH2 Domain Mutants In Cancer Pathway (1000712); SMAD2/3 Phosphorylation Motif Mutants In Cancer Pathway (1000711); SMAD4 MH2 Domain Mutants In Cancer Pathway (1000705); Signal Transduction Pathway (970540); Signaling By TGF-beta Receptor Complex Pathway (1000706)
uniprot summary :
NEDD8: a member of the ubiquitin family of proteins. Approximately 60% identical to ubiquitin protein. Activated by an E1-like complex, consisting of App-b1 and Uba3 and then linked to the E2-like enzyme, Ubc12. The major target protein modified by nedd8 is cullin-4a. Down-regulated during the development of brain. Protein type: Ubiquitin-like modifier. Cellular Component: nucleus. Molecular Function: protein binding; ubiquitin protein ligase binding. Biological Process: regulation of transcription from RNA polymerase II promoter; protein localization; protein neddylation; response to organic cyclic substance
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)